284661-57-0

Basic information

• Product Name: tert-butyl (2R,3S)-3-(dibenzylamino)-2-hydroxy-4-phenylbutyl(isobutyl)carbamate
• Synonyms: tert-butyl (2R,3S)-3-(dibenzylamino)-2-hydroxy-4-phenylbutyl(isobutyl)carbamate
• CAS NO: 284661-57-0
• Molecular Weight: 516.724
• Mol File: 284661-57-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl (2R,3S)-3-(dibenzylamino)-2-hydroxy-4-phenylbutyl(isobutyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (2R,3S)-3-(dibenzylamino)-2-hydroxy-4-phenylbutyl(isobutyl)carbamate(284661-57-0)
• EPA Substance Registry System: tert-butyl (2R,3S)-3-(dibenzylamino)-2-hydroxy-4-phenylbutyl(isobutyl)carbamate(284661-57-0)

Safety Data

• Hazardous Substances Data: 284661-57-0(Hazardous Substances Data)

Upstream product

• 174391-93-6 N-[3(S)-[N,N-bis(phenylmethyl) amino]-2(R)-hydroxy-4-phenylbutyl]-N-isobutylamine. oxalic acid salt 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 183554-00-9 tert-butyl (2R,3S)-3-amino-2-hydroxy-4-phenylbutyl(isobutyl)carbamate 

Relevant articles and documents

AMIDE COMPOUNDS AS BOOSTERS OF ANTIVIRALS

The present invention relates to compounds that have CYP450 inhibiting properties and are therefore useful as boosters of certain drugs, i.e. they are able to increase at least one of the pharmacokinetic variables of certain drugs when co-administered. The invention further provides the use of said compounds as improvers of the bioavailability of certain drugs. Methods for the preparation of the compounds of the invention and pharmaceutical compositions are also provided.