285-59-6

Basic information

• Product Name: 3-azabicyclo[3.1.0]hexane
• Synonyms: 3-azabicyclo[3.1.0]hexane;UKRORGSYN-BB BBV-265866
• CAS NO: 285-59-6
• Molecular Formula: C₅H₉N
• Molecular Weight: 83.13
• Product Categories: CHIRAL CHEMICALS
• Mol File: 285-59-6.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-azabicyclo[3.1.0]hexane(CAS DataBase Reference)
• NIST Chemistry Reference: 3-azabicyclo[3.1.0]hexane(285-59-6)
• EPA Substance Registry System: 3-azabicyclo[3.1.0]hexane(285-59-6)

Safety Data

• Hazardous Substances Data: 285-59-6(Hazardous Substances Data)

Usage

General Description

3-Azabicyclo[3.1.0]hexane, also known as norbornane, is a bicyclic organic compound with the chemical formula C7H12. It is a white crystalline solid at room temperature and is considered to be a saturated analog of aziridine. 3-Azabicyclo[3.1.0]hexane is used in organic synthesis as a building block for various compounds and as a solvent in organic reactions. It is also used as a precursor in the production of pharmaceuticals and agrochemicals. The compound has potential applications in the development of new materials and has been studied for its potential use as a drug delivery system. Additionally, it has shown promise in the field of asymmetric synthesis due to its unique chemical structure. Overall, 3-Azabicyclo[3.1.0]hexane has a wide range of applications in the chemical and pharmaceutical industries.

Upstream product

• 73799-64-1 3-azabicyclo[3.1.0]hexane hydrochloride 
• 73799-64-1 3-Azabicyclo<3.1.0>hexane hydrochloride 
• 73799-63-0 3-benzyl-3-aza-bicyclo[3.1.0]hexane-2,4-dione 
• 710-43-0 cis-cyclopropane-1,2-dicarboxylic acid diethyl ester 
• 696-74-2 cis-1,2-cyclopropanedicarboxylic acid 
• 5617-74-3 3-oxabicyclo[3.1.0]hexane-2,4-dione 
• 70110-45-1 3-benzyl-3-aza-bicyclo[3.1.0]hexane 
• 5617-69-6 3-aza-bicyclo[3.1.0]hexane-2,4-dione 

Downstream Products

• 115182-91-7 3-azabicyclo-(3.1.0)hexane-2-carbonitrile 
• 681425-48-9 [4-(3-azabicyclo[3.1.0]hex-3-yl)-3,5-difluorophenyl]carbamic acid benzyl ester 
• 681425-51-4 [4-(3-azabicyclo[3.1.0]hex-3-yl)-3-fluorophenyl]carbamic acid benzyl ester 
• 681425-50-3 4-(3-aza-bicyclo[3.1.0]hex-3-yl)-3,5-difluoro-phenylamine 
• 681425-53-6 4-(3-aza-bicyclo[3.1.0]hex-3-yl)-3-fluoro-phenylamine 
• 681425-49-0 3-(2,6-difluoro-4-nitrophenyl)-3-azabicyclo[3.1.0]hexane 
• 681425-52-5 3-(2-fluoro-4-nitrophenyl)-3-azabicyclo[3.1.0]hexane 

Relevant articles and documents

High Resolution 1H NMR Studies of Cyclic N-Nitrosoamines

Molecular modeling by molecular mechanics (MM2) calculations were used to predict conformational preferences of cyclic N-nitrosoamines.The results were compared with 1H NMR data.The observed geminal coupling constants 2J were considerably stronger for syn than for anti α-methylene protons and thus appear to be very useful for configurational predictions.The long-range 4J couplings across the nitrogen atom were observed directly from the 1D spectra. - Keywords: NMR 1H NMR Molecular modeling Cyclic N-Nitrosamines 1H,1H Spin-Spin coupling

NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS AND THE USES THEREOF

The invention relates to pyridinyl nicotinic acetylcholine receptor ligands, compositions comprising an effective amount of a pyridinyl nicotinic acetylcholine receptor ligand and methods to treat or prevent a condition, such as depression and nicotine dependence, comprising administering to an animal in need thereof an effective amount of a pyridinyl nicotinic acetylcholine receptor ligand.

Potent non-nitrile dipeptidic dipeptidyl peptidase IV inhibitors

The synthesis and structure-activity relationships of novel dipeptidyl peptidase IV inhibitors replacing the classical cyanopyrrolidine P1 group with other small nitrogen heterocycles are described. A unique potency enhancement was achieved with β-branched natural and unnatural amino acids, particularly adamantylglycines, linked to a (2S,3R)-2,3-methanopyrrolidine based scaffold.