287114-32-3

Basic information

• Product Name: 1-(2-Pyridinyl)hexahydro-1H-1,4-diazepine
• Synonyms: 1-PYRIDINE-2-YL-[1,4]-DIAZEPANE;1-(2-Pyridinyl)hexahydro-1H-1,4-diazepine;1-(2-Pyridyl)homopiperazine
• CAS NO: 287114-32-3
• Molecular Formula: C₁₀H₁₅N₃
• Molecular Weight: 177.25
• Product Categories: pharmacetical
• Mol File: 287114-32-3.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 104℃/0.4mm
• Flash Point: 150.036 °C
• Appearance: /
• Density: 1.05 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.535
• Storage Temp.: 2-8°C
• PKA: 10.34±0.20(Predicted)
• Sensitive: Air Sensitive
• CAS DataBase Reference: 1-(2-Pyridinyl)hexahydro-1H-1,4-diazepine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Pyridinyl)hexahydro-1H-1,4-diazepine(287114-32-3)
• EPA Substance Registry System: 1-(2-Pyridinyl)hexahydro-1H-1,4-diazepine(287114-32-3)

Safety Data

• HazardClass: 8
• Hazardous Substances Data: 287114-32-3(Hazardous Substances Data)

Usage

General Description

1-(2-Pyridinyl)hexahydro-1H-1,4-diazepine, also known as 2-Pyridyl-1,4-hexahydropyrazine, is a chemical compound with the molecular formula C11H18N2. It is a heterocyclic compound containing a six-membered ring with alternating carbon and nitrogen atoms, as well as a pyridine ring attached to the ring. 1-(2-Pyridinyl)hexahydro-1H-1,4-diazepine has potential applications in the field of pharmaceuticals, as it exhibits biological activity against certain pathogens and can be used as a building block in the synthesis of various compounds. Its unique structure gives it the potential to act as a versatile intermediate in organic synthesis and drug discovery research.

InChI:InChI=1/C10H15N3/c1-2-6-12-10(4-1)13-8-3-5-11-7-9-13/h1-2,4,6,11H,3,5,7-9H2

Upstream product

• 505-66-8 1,4-Diazacycloheptane 
• 109-04-6 2-bromo-pyridine 
• 112275-50-0 tert-butyl 1,4-diazepine-1-carboxylate 
• 632334-60-2 tert-butyl 4-(2-pyridyl)-1,4-diazepane-1-carboxylate 
• 13716-12-6 tri-tert-butyl phosphine 
• 109-09-1 2-chloropyridine 

Downstream Products

• 112275-50-0 tert-butyl 1,4-diazepine-1-carboxylate 
• 1373271-02-3 1-{1-[(2-chlorophenyl)methyl]piperidin-4-yl}-4-(pyridin-2-yl)-1,4-diazepane 
• 1609534-94-2 1,1-diethyl-4-(2-pyridyl)-homopiperazinium tosylate 

Relevant articles and documents

METHOD FOR USE OF HOMOPIPERAZINIUM COMPOUNDS IN THE TREATMENT OF CANCER

The present disclosure relates to a method for treating cancer comprising administering to a patient in need thereof an effective amount of a compound having the formula: (Formula (I)) wherein R1, R2, Ya, Xa, and J- are as defined herein.

CXCR4 Receptor Antagonists

Disclosed are compounds that are antagonists of the CXCR4 receptor.

THIENOPYRIDINE DERIVATIVES

The present invention provides a compound promoting osteogenesis. The present invention provides a compound having the following general formula (I) wherein R 1 is H or alkyl, R 2 is R a S-, R a O-, R a NH-, R a (R b )N- or cyclic amino, and R a and R b are alkyl which may be substituted, cycloalkyl which may be substituted, or the like, or a pharmacologically acceptable salt thereof.