287402-09-9Relevant articles and documents
COMBINATION PRODUCT COMPRISING DICYCLOPLATIN AND PREPARATION METHOD AND USE THEREOF
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Paragraph 0067-0074, (2020/12/04)
The present invention relates to the compositions containing dicycloplatin, pharmaceutical use of the compositions in the treatment and/or prevention of pain, inflammation and virus-related diseases, and methods of preparing the compostions thereof.
Method for synthesizing dicycloplatin by microwave catalysis
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Paragraph 0023-0024; 0026, (2017/09/01)
The invention discloses a method for synthesizing dicycloplatin by microwave catalysis. The method comprises the steps: mixing carboplatin and 1,1-cyclobutane dicarboxylic acid in a corresponding ratio as well as a solvent; according to a molar ratio of the carboplatin to the 1,1-cyclobutane dicarboxylic acid of 1:(1 to 1.5), performing a reaction for 9 minutes in microwaves, controlling a temperature of 30 DEG C, then carrying out decompressing condensing at a temperature of 35 DEG C, washing a filter cake with ethyl alcohol, and after vacuum drying, obtaining the dicycloplatin. The method disclosed by the invention has the advantages of convenience for operation, mild reaction condition, short reaction time, high reproducibility ad high product purity.