287952-08-3 Usage
Description
N-BOC-4-(4-trifluoromethylphenoxy)piperidine is a piperidine derivative featuring a BOC (tert-butyloxycarbonyl) protecting group on the nitrogen atom and a 4-(4-trifluoromethylphenoxy) substituent on the piperidine ring. This chemical compound serves as a versatile building block in organic synthesis and pharmaceutical research, known for its potential in creating various pharmaceuticals and biologically active molecules.
Uses
Used in Pharmaceutical Research:
N-BOC-4-(4-trifluoromethylphenoxy)piperidine is used as a key intermediate in the synthesis of pharmaceuticals for its ability to be incorporated into complex molecular structures, contributing to the development of new drugs with potential therapeutic applications.
Used in Organic Chemistry:
In the field of organic chemistry, N-BOC-4-(4-trifluoromethylphenoxy)piperidine is utilized as a reagent for the introduction of piperidine-based motifs into molecules. This enhances the structural diversity and functional groups available for further chemical reactions and the creation of novel compounds.
Used in the Synthesis of Biologically Active Molecules:
N-BOC-4-(4-trifluoromethylphenoxy)piperidine is employed as a precursor in the synthesis of biologically active molecules, leveraging its structural features to produce compounds with potential applications in medicine and biology.
Overall, N-BOC-4-(4-trifluoromethylphenoxy)piperidine is a valuable compound with diverse applications across chemical and pharmaceutical research, playing a crucial role in the development of new drugs and the advancement of organic chemistry techniques.
Check Digit Verification of cas no
The CAS Registry Mumber 287952-08-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,7,9,5 and 2 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 287952-08:
(8*2)+(7*8)+(6*7)+(5*9)+(4*5)+(3*2)+(2*0)+(1*8)=193
193 % 10 = 3
So 287952-08-3 is a valid CAS Registry Number.
287952-08-3Relevant articles and documents
Palladium Catalyzed C?O Coupling of Amino Alcohols for the Synthesis of Aryl Ethers
Mikus, Malte S.,Sanchez, Carina,Fridrich, Cary,Larrow, Jay F.
supporting information, p. 430 - 436 (2019/12/27)
Amine containing aryl ethers are common pharmacophore motifs that continue to emerge from drug discovery efforts. As amino alcohols are readily available building blocks, practical methodologies for incorporating them into more complex structures are highly desirable. We report our efforts to explore the application of Pd-catalyzed C?O coupling methods to the arylation of 1,2- and 1,3-amino alcohols. We established general and reliable conditions, under which we explored the scope and limitations of the transformation. The insights gained have been valuable in employing this methodology within a fast-moving drug discovery environment, which we anticipate will be of general interest to the synthesis and catalysis communities.
Sulfamato hydroxamic acid metalloprotease inhibitor
-
, (2008/06/13)
A sulfamato hydroxamic acid compound that, inter alia, inhibits matrix metalloprotease (mmp) activity is disclosed as are a process for preparing the same, intermediate compounds useful in those syntheses, and a treatment process that comprises administering a contemplated sulfamato hydroxamic acid compound in a MMP enzyme-inhibiting effective amount to a host having a condition associated with pathological matrix metalloprotease activity.
