288851-44-5 Usage
Description
4-(3-Carboxy-propionyl)-piperazine-1-carboxylic acid tert-butyl ester is a versatile ester compound characterized by the presence of a piperazine ring and a carboxylic acid functional group, along with a tert-butyl ester. It is an organic compound derived from an acid where at least one -OH (hydroxyl) group is substituted by an -O-alkyl group. The tert-butyl ester group in this compound acts as a protective group for the carboxylic acid, enabling selective reactions and preventing unwanted interactions.
Uses
Used in Pharmaceutical Synthesis:
4-(3-Carboxy-propionyl)-piperazine-1-carboxylic acid tert-butyl ester is used as a building block in the synthesis of pharmaceuticals. Its unique structure and functional groups make it a valuable component in the development of new drugs and therapeutic agents.
Used in Agrochemical Production:
4-(3-CARBOXY-PROPIONYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is also utilized in the production of agrochemicals, where it serves as a key intermediate in the synthesis of various pesticides and other agricultural chemicals.
Used in Polymer and Material Science:
4-(3-Carboxy-propionyl)-piperazine-1-carboxylic acid tert-butyl ester is employed in the field of polymer and material science for the production of different types of polymers and materials. Its versatility and reactivity contribute to the creation of innovative materials with specific properties for various applications.
Used in Organic Chemistry Research:
As a versatile ester compound, 4-(3-Carboxy-propionyl)-piperazine-1-carboxylic acid tert-butyl ester is used in organic chemistry research for studying reaction mechanisms, exploring new synthetic routes, and developing novel chemical transformations.
Check Digit Verification of cas no
The CAS Registry Mumber 288851-44-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,8,8,5 and 1 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 288851-44:
(8*2)+(7*8)+(6*8)+(5*8)+(4*5)+(3*1)+(2*4)+(1*4)=195
195 % 10 = 5
So 288851-44-5 is a valid CAS Registry Number.
InChI:InChI=1/C13H22N2O5/c1-13(2,3)20-12(19)15-8-6-14(7-9-15)10(16)4-5-11(17)18/h4-9H2,1-3H3,(H,17,18)
288851-44-5Relevant articles and documents
Calcium-promoted hydrolysis of N-acylureas allows mild release of peptides anchored with Dpr(Phoc) linker to hydrophilic resins
Pascal, Robert,Sola, Regine
, p. 4549 - 4552 (1997)
Calcium chloride is an efficient additive for promoting the release of short peptide models anchored with Dpr(Phoc) linker to hydrophilic solid-phase synthesis supports. It was shown to induce a moderate to marked (especially for C-terminal proline peptides) increase in the rate of alkaline hydrolytic cleavage, without epimerization at the C-terminal residue, while substantially reducing the hydroxide ion concentration. Base-promoted side-reactions are therefore expected to be slowed down.
Synthesis and antiaggregation activity of a new RGDF peptidomimetic
Krys'ko,Kabanov,Polishchuk,Chugunov,Pavlovskii,Andronati,Mazepa,Kabanova,Karaseva
, p. 948 - 952 (2007/10/03)
A new RGDF peptidomimetic, [4-oxo-4-(pyperazin-1-yl)butyryl]glycyl-D,L-β-phenyl-β-alanine was synthesized. The arginyl mimetic used was the 4-oxo-4-(piperazin-1-yl)butanoic acid residue, and the Asp-Phe chain is replaced by a β-phenyl-β-alanine residue. The synthesized pseudopeptide showed ability to inhibite ADF-induced thrombocyte aggregation in a thrombocyte-rich rat blood plasma (IC50 8.7 × 10-9 M).
