28957-33-7

Basic information

• Product Name: D-alpha-Amino-epsilon-caprolactam
• Synonyms: 2H-Azepin-2-one, 3-aminohexahydro-, (R)-;(3R)-3-aminoazepan-2-one;(2R)-2,6-Diaminohexanoic acid 1,6-lactam;(3R)-3α-Aminohexahydro-1H-azepine-2-one;(3R)-3α-Aminohexahydro-2H-azepine-2-one;(R)-3-Aminohexahydro-1H-azepin-2-one;[R,(+)]-3-Aminohexahydro-1H-azepin-2-one;(R)-3-Amino-Hexahydro-1H-Azepin
• CAS NO: 28957-33-7
• Molecular Formula: C₆H₁₂N₂O
• Molecular Weight: 128.17
• EINECS: 1533716-785-6
• Mol File: 28957-33-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 97-101 °C
• Boiling Point: 315.124 °C at 760 mmHg
• Flash Point: 144.382 °C
• Appearance: /
• Density: 1.031 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 16.06±0.40(Predicted)
• CAS DataBase Reference: D-alpha-Amino-epsilon-caprolactam(CAS DataBase Reference)
• NIST Chemistry Reference: D-alpha-Amino-epsilon-caprolactam(28957-33-7)
• EPA Substance Registry System: D-alpha-Amino-epsilon-caprolactam(28957-33-7)

Safety Data

• RIDADR: 1759
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 28957-33-7(Hazardous Substances Data)

Usage

General Description

D-alpha-Amino-epsilon-caprolactam is a chemical compound that pertains to the alpha amino group and is a derivative of caprolactam, which is a colorless organic compound widely used in the production of nylon. It is often used in a variety of industrial applications such as the production of plastics and synthetic fibers. Due to its unique properties and chemical structure, D-alpha-Amino-epsilon-caprolactam plays a vital role in molecular biology and chemical research. Its specific properties can influence physical aspects like melting point, density and solubility, making it valuable in various chemical reactions. Despite its benefits in industry, it must be handled carefully due to potential hazards associated with its improper use.

Upstream product

• 17929-90-7 3-aminoazepan-2-one 
• 6804-88-2 α-nitrocaprolactam 

Downstream Products

• 13122-23-1 D(+)-α-Phthalimido-ε-caprolactam 
• 179535-30-9 (R)-3-(Trityl-amino)-azepan-2-one 
• 106691-72-9 3(R)--2-oxoperhydroazepine 
• 124932-43-0 (R)-(+)-3-Amino-hexahydro-1H-azepin 
• 1415251-17-0 C₃₈H₅₇N₉O₈ 
• 1067659-02-2 tert-butyl methyl((R)-azepan-2-one-3-ylamino-(R)-oxo-3-phenylpropan-2-yl)carbamate 
• 1067658-96-1 tert-butyl methyl((R)-azepan-2-one-3-ylamino-(S)-oxo-3-phenylpropan-2-yl)carbamate 
• 16851-56-2 indolin-2-yl carboxylic acid 
• 179686-45-4 3-(S)-tert-butoxycarbonylamino-4,5,6,7-tetrahydroazepin-2-one 
• 131926-36-8 D(-)-α-Phthalimidoadipinimide 
• 146349-40-8 methyl 3(R)-<<<1-(benzyloxycarbonyl)-2(S)-pyrrolidinyl>carbonyl>amino>-2-oxo-1-perhydroazepineacetate 
• 146349-31-7 3(R)-<<<1-(benzyloxycarbonyl)-2(S)-pyrrolidinyl>carbonyl>amino>-2-oxo-1-perhydroazepineacetamide 
• 16509-61-8 (R)-2-amino-6-hydroxy-hexanoic acid 

Relevant articles and documents

SEPARATING AGENT FOR CHROMATOGRAPHY

A separating agent for chromatography is provided that is useful for the separation of specific compounds, e.g., for the optical resolution of amino acids. This separating agent for chromatography provides a higher productivity and contains a crown ether-like cyclic structure and optically active binaphthyl. This separating agent for chromatography containing a crown ether-like cyclic structure and optically active binaphthyl is provided by introducing a substitution group for binding to carrier into a specific commercially available 1,1′-binaphthyl derivative that has substituents at the 2, 2′, 3, and 3′ positions, then introducing a crown ether-like cyclic structure, and subsequently chemically bonding the binaphthyl derivative to the carrier through the substitution group for binding to carrier.

Resolution of α-aminolactams by inclusion complexation with chiral host compounds

3-Aminopiperidin-2-one and α-amino-ε-caprolactam were efficiently resolved by inclusion complexation with a chiral host compound, (R,R)-(-)-trans-4,5-bis(hydroxydiphenylmethyl)-1,4-dioxaspiro[4.5]decane . The amino substituent on the lactam ring was found to play an important role in efficient chiral recognition in the inclusion crystals.

ASYMMETRIC CATALYTIC SYNTHESIS OF LYSINE BY HYDROGENATION OF α-NITROCAPROLACTAM

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