289910-65-2 Usage
General Description
Boc-Tyr(tBu)-Pro-OH is a chemical compound consisting of a Boc-protected tyrosine, a tert-butyl-protected proline, and a carboxylic acid group. Boc (tert-butoxycarbonyl) and tBu (tert-butyl) are both protective groups commonly used in peptide synthesis to temporarily block reactive functional groups and protect them from unwanted reactions. Boc-Tyr(tBu)-Pro-OH is often used as a building block in the synthesis of peptides and small molecules in organic chemistry. The Boc group can be easily removed under mild acidic conditions, making it a versatile and widely-used protective group in peptide synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 289910-65-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,9,9,1 and 0 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 289910-65:
(8*2)+(7*8)+(6*9)+(5*9)+(4*1)+(3*0)+(2*6)+(1*5)=192
192 % 10 = 2
So 289910-65-2 is a valid CAS Registry Number.
289910-65-2Relevant articles and documents
β-Casomorphins: Substitution of phenylalanine with β-homo phenylalanine increases the μ-type opioid receptor affinity
Longobardo, Luigi,Melck, Dominique,Siciliano, Rosa,Santini, Antonello,Marzo, Vincenzo Di,Cammarota, Giancarlo
, p. 1185 - 1188 (2007/10/03)
Two analogues of bovine β-casomorphin-7 and β-casomorphin-5 containing a β-homo phenylalanine in substitution of the phenylalanine in position 3 were synthesised and tested for their μ-opioid receptor affinity. The modification enhanced the μ receptor affinity 5-fold in the case of modified β-CM-7 and 2-fold for modified β-CM-5 when compared to the natural peptides. (C) 2000 Elsevier Science Ltd. All rights reserved.