290308-58-6

Basic information

• Product Name: Succinic acid benzyl ester (2R,3R,4R,5R,6R)-3,4-diacetoxy-5-acetylamino-6-[6-(9H-fluoren-9-ylmethoxycarbonylamino)-hexyloxy]-tetrahydro-pyran-2-ylmethyl ester
• Synonyms: Succinic acid benzyl ester (2R,3R,4R,5R,6R)-3,4-diacetoxy-5-acetylamino-6-[6-(9H-fluoren-9-ylmethoxycarbonylamino)-hexyloxy]-tetrahydro-pyran-2-ylmethyl ester
• CAS NO: 290308-58-6
• Molecular Weight: 816.902
• Mol File: 290308-58-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Succinic acid benzyl ester (2R,3R,4R,5R,6R)-3,4-diacetoxy-5-acetylamino-6-[6-(9H-fluoren-9-ylmethoxycarbonylamino)-hexyloxy]-tetrahydro-pyran-2-ylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Succinic acid benzyl ester (2R,3R,4R,5R,6R)-3,4-diacetoxy-5-acetylamino-6-[6-(9H-fluoren-9-ylmethoxycarbonylamino)-hexyloxy]-tetrahydro-pyran-2-ylmethyl ester(290308-58-6)
• EPA Substance Registry System: Succinic acid benzyl ester (2R,3R,4R,5R,6R)-3,4-diacetoxy-5-acetylamino-6-[6-(9H-fluoren-9-ylmethoxycarbonylamino)-hexyloxy]-tetrahydro-pyran-2-ylmethyl ester(290308-58-6)

Safety Data

• Hazardous Substances Data: 290308-58-6(Hazardous Substances Data)

Upstream product

• 127903-20-2 9H-fluoren-9-ylmethyl N-(6-hydroxyhexyl)carbamate 
• 290308-57-5 Succinic acid benzyl ester (2R,3R,4R,5R,6R)-3,4,6-triacetoxy-5-acetylamino-tetrahydro-pyran-2-ylmethyl ester 

Relevant articles and documents

Facile solid phase synthesis of YEE(ah-GalNAc)3, a ligand with known high affinity for the asialoglycoprotein receptor

A simple cluster glycoside, containing three residues of N- acetylgalactosamine with proper inter-residual distances, can be a high- affinity ligand for the asialoglycoprotein receptor (ASGPr) of mammalian liver. Tris(GalNAc-aminohexyl)glycoside of tyrosyl(glutamyl)glutamate YEE(ah- GalNAc)3 1, which is known to have sub-nanomolar affinity for the asialoglycoprotein receptor, was efficiently synthesized by using succinic acid as a linker to anchor GalNAc-aminohexyl glycoside to solid phase resin, followed by coupling the building blocks of Fmoc-(ah-α-GalNAcAc3)Glu and Fmoc-Tyr-OH to obtain YEE(ah-GalNAc)3 with a total yield of 83%.