29098-15-5 Usage
Originator
Etofen Ilfi,Lusofarmaco,Italy,1980
Manufacturing Process
10 g sodium salt of N-2,6-dichloro-m-tolylanthranilic acid, 3 ml chloromethyl
ethyl ether and 80 ml dry acetone were refluxed for 12 hours on waterbath
under stirring. The solid was filtered off, and the solution evaporated to
dryness. The residue was dissolved in chloroform, washed with sodium
carbonate solution, then with water until neutral. After drying on sodium
sulfate, the solution was evaporated to dryness. The obtained product was
recrystallized from 95% ethanol. Melting point 73°C to 74°C.
Therapeutic Function
Antiinflammatory, Analgesic
Check Digit Verification of cas no
The CAS Registry Mumber 29098-15-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,9,0,9 and 8 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 29098-15:
(7*2)+(6*9)+(5*0)+(4*9)+(3*8)+(2*1)+(1*5)=135
135 % 10 = 5
So 29098-15-5 is a valid CAS Registry Number.
InChI:InChI=1/C17H17Cl2NO3/c1-3-22-10-23-17(21)12-6-4-5-7-14(12)20-16-13(18)9-8-11(2)15(16)19/h4-9,20H,3,10H2,1-2H3
29098-15-5Relevant articles and documents
New esters of N arylanthranilic acids
Salimbeni,Manghisi,Magistretti
, p. 276 - 286 (2007/10/06)
A series of acyloxy and alkyloxymethyl esters of meclofenamic, flufenamic and mefenamic acids has been synthesized and its antiinflammatory, analgesic and antipyretic activities have been compared with those of the corresponding acids and the methyl, β,γ isopropylidenedioxypropyl, and N,N diethylaminoethyl esters. The acyloxy and alkyloxymethyl esters are the most interesting compounds, because they possess pharmacological activity of the same order as that of the corresponding acids and a lower toxicity. The ethoxymethyl ester of N (2,6 dichloro m tolyl)anthranilic acid is presently under clinical investigation.
