2917-91-1Relevant articles and documents
LE CHLOROALLYLLITHIUM COMME SYNTHON DE CHLOROALLYLATION OU COMME EQUIVALENT DU VINYLCARBENE: SYNTHESE REGIOSELECTIVE D'ALCOOLS γ-ETHYLENIQUES β-CHLORES ET DE VINYL-2 OXETANES A PARTIR D'EPOXYDES
Ongoka, P.,Mauze, B.,Miginiac, L.
, p. 139 - 148 (1985)
Chloroallyllithium reacts regioselectively with various epoxides in a "one-pot" reaction to produce either γ-ethylenic β-chloro alcohols or 2-vinyl oxetanes, depending on the experimental conditions used.
Treatment of excessive osteolysis with indolinone compounds
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, (2008/06/13)
Compounds of Formula I and Formula II, as described herein, are useful for treating excessive osteolysis, by inhibiting M-CSF mediated osteoclast development. The compounds also are useful for inhibiting phosphorylation of CSF1R, and for treating cancers that express CSF1R.
Treatment of acute myeloid leukemia with indolinone compounds
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, (2008/06/13)
A method of treating acute myeloid leukemia in patient positive for FLT-3-ITD is described. The treatment is accomplished by administration of a compound of Formula I or II as defined herein.