2918-67-4

Basic information

• Product Name: N-CYCLOHEXYL METHACRYLAMIDE
• Synonyms: N-CYCLOHEXYL METHACRYLAMIDE;CYCLOHEXYL METHACRYLAMIDE;N-cyclohexyl-2-methyl-acrylamide;N-cyclohexyl-2-methyl-prop-2-enamide;N-cyclohexyl-2-methylprop-2-enamide
• CAS NO: 2918-67-4
• Molecular Formula: C₁₀H₁₇NO
• Molecular Weight: 167.25
• EINECS: 220-853-4
• Product Categories: monomer
• Mol File: 2918-67-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 319.2°Cat760mmHg
• Flash Point: 187.6°C
• Appearance: /
• Density: 0.95g/cm³
• Vapor Pressure: 0.000345mmHg at 25°C
• Refractive Index: 1.475
• CAS DataBase Reference: N-CYCLOHEXYL METHACRYLAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-CYCLOHEXYL METHACRYLAMIDE(2918-67-4)
• EPA Substance Registry System: N-CYCLOHEXYL METHACRYLAMIDE(2918-67-4)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 2918-67-4(Hazardous Substances Data)

Usage

General Description

N-Cyclohexyl methacrylamide is a chemical compound that is a member of the methacrylamide family. It is commonly used in the synthesis and production of various polymers and resins. N-CYCLOHEXYL METHACRYLAMIDE is a clear, colorless liquid or solid, with a slight odor, and is soluble in organic solvents. N-Cyclohexyl methacrylamide is utilized in industries such as adhesives, coatings, and sealants, where it contributes to the strength and durability of these materials. Additionally, it is also used in the production of specialty chemicals and pharmaceuticals. This chemical is known to have low toxicity and is considered safe for use in appropriate industrial applications.

InChI:InChI=1/C10H17NO/c1-8(2)10(12)11-9-6-4-3-5-7-9/h9H,1,3-7H2,2H3,(H,11,12)

Upstream product

• 108-91-8 cyclohexylamine 
• 920-46-7 Methacryloyl chloride 
• 110228-40-5 2-bromo-2-methyl-N-cyclohexylpropanamide 
• 21043-40-3 1-cyclopentylpiperazine 
• 79-41-4 poly(methacrylic acid) 
• 108-94-1 cyclohexanone 
• 463-49-0 1,2-propanediene 
• 201230-82-2 carbon monoxide 

Downstream Products

• 1326317-57-0 potassium N-cyclohexyl-2-methyl-3-(trifluoroborato)propanamide 
• 1450754-09-2 (Z)-N-[3-(cyclohexylamino)-2-methyl-3-oxoprop-1-enyl]-4-nitrobenzamide 
• 1414882-47-5 (2E,4Z)-n-butyl 6-cyclohexylamino-5-methyl-6-oxohexa-2,4-dienoate 
• 1309763-11-8 1-cyclohexyl-3-methyl-5,6-diphenylpyridin-2(1H)-one 

Relevant articles and documents

Effect of Transition Metals on Chemodivergent Cross-Coupling of Acrylamides with Vinyl Acetate via C-H Activation

A novel chemodivergent cross-coupling of acrylamides and vinyl acetates has been realized via metal-catalyzed vinylic C-H activation. The selective olefinic C-H vinylation and alkenylation reaction was examined with a variety of differently functionalized acrylamides. The reaction efficiently generates a range of highly synthetically valuable butadienes with good functional group tolerance in good to moderate yields. A possible catalytic reaction mechanism involving the chelation-assisted olefinic C-H activation via an acetate-assisted deprotonation pathway is proposed.

Favorskii-like rearrangement of an aliphatic α-halo amide

The reaction of the α-bromoamide 2a with 1-cyclopentylpiperazine gives the Favorskii-like rearranged product 4 when the reaction is heated to 70 °C in a mixture of aqueous potassium hydroxide and ethanol. However, when solid sodium carbonate/potassium iodide is used in ethanol, the nonrearranged product 3a is formed instead. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications to view the free supplemental file.

Copper-catalyzed β-boration of α,β-unsaturated carbonyl compounds with tetrahydroxydiborane

The copper-catalyzed β-boration of α,β-unsaturated carbonyl compounds with tetrahydroxydiborane has been developed. This diboron reagent allows direct, efficient access to boronic acids and their derivatives. Primary, secondary, and tertiary α,β-unsaturated amides are converted to the corresponding β-trifluoroboratoamides in good to excellent yields. The β-boration of a variety of α,β-unsaturated esters and ketones is also reported.