2918-77-6

Basic information

• Product Name: N-(4-CHLOROPHENYL) METHACRYLAMIDE
• Synonyms: N-(4-CHLOROPHENYL)-2-METHYLACRYLAMIDE;N-(4-CHLOROPHENYL) METHACRYLAMIDE
• CAS NO: 2918-77-6
• Molecular Formula: C₁₀H₁₀ClNO
• Molecular Weight: 195.65
• Product Categories: monomer
• Mol File: 2918-77-6.mol
• Article Data: 35

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(4-CHLOROPHENYL) METHACRYLAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-CHLOROPHENYL) METHACRYLAMIDE(2918-77-6)
• EPA Substance Registry System: N-(4-CHLOROPHENYL) METHACRYLAMIDE(2918-77-6)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 2918-77-6(Hazardous Substances Data)

Upstream product

• 1970-52-1 2-bromo-2-methyl-N-(p-chlorophenyl)propanamide 
• 51491-68-0 2-phenylacrylyl chloride 
• 106-47-8 4-chloro-aniline 
• 79-41-4 poly(methacrylic acid) 
• 920-46-7 Methacryloyl chloride 

Downstream Products

• 126335-18-0 3-Chloro-N-(4-chloro-phenyl)-2-methyl-2-methylsulfanyl-propionamide 
• 1588429-75-7 5-chloro-1, 3-dimethyl-3-((phenylsulfonyl)methyl)indolin-2-one 
• 1414882-53-3 (2E,4Z)-n-butyl 6-p-chlorophenylamino-5-methyl-6-oxohexa-2,4-dienoate 
• 1256971-27-3 C₂₄H₁₈ClNO 

Relevant articles and documents

Bromo Radical-Mediated Photoredox Aldehyde Decarbonylation towards Transition-Metal-Free Hydroalkylation of Acrylamides at Room Temperature

Herein, we report a visible-light-mediated hydroalkylation reaction of alkenes using easily available aldehydes as alkyl sources via bromo radical-promoted photoredox decarbonylation. This protocol provides an alternative entry to C(sp3)?C(sp3) bond formation and features considerable advantages including mild and clean reaction conditions, obviation for transition-metal catalyst, and good functional group compatibility.

A benzene-bridged divanadium complex-early transition metal catalyst for alkene alkylarylation with PhI(O2CR)2viadecarboxylation

The synthesis, structure and catalytic activity of a benzene-bridged divanadium complex were comprehensively studied. The reduction of (Nacnac)VCl2(1) (Nacnac = (2,6-iPr2C6H3NCMe)2HC) supported by β-diketiminate with potassium graphite (KC8) by employing benzene as the solvent allows access to the benzene-bridged inverted-sandwich divanadium complex (μ-η6:η6-C6H6)[V(Nacnac)]2(2a), which can catalyze alkene alkylarylation with hypervalent iodine(iii) reagents (HIRs)viadecarboxylation to generate regioselectively diverse indolinones. Furthermore, the mild nature of this reaction was amenable to a wide range of functionalities on alkenes and HIRs. Mechanistic studies revealed a relay sequence of decarboxylative radical alkylation/radical arylation/oxidative re-aromatization.

Copper-Catalyzed Radical N-Demethylation of Amides Using N-Fluorobenzenesulfonimide as an Oxidant

An unprecedented N-demethylation of N-methyl amides has been developed by use of N-fluorobenzenesulfonimide as an oxidant with the aid of a copper catalyst. The conversion of amides to carbinolamines involves successive single-electron transfer, hydrogen-atom transfer, and hydrolysis, and is accompanied by formation of N-(phenylsulfonyl)benzenesulfonamide. Carbinolamines spontaneously decompose to N-demethylated amides and formaldehyde, because of their inherent instability.