2922-56-7

Basic information

• Product Name: S-METHYLGLUTATHIONE
• Synonyms: S-METHYLGLUTATHIONE;L-γGlu-S-Methyl-L-Cys-Gly-OH;γGlu-3-(Methylthio)-Ala-Gly-OH;(2S)-2-amino-5-[[(1R)-2-(carboxymethylamino)-2-keto-1-[(methylthio)methyl]ethyl]amino]-5-keto-valeric acid;(2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-3-methylsulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acid;(2S)-2-azanyl-5-[[(2R)-1-(carboxymethylamino)-3-methylsulfanyl-1-oxo-propan-2-yl]amino]-5-oxo-pentanoic acid;S-methyl-GSH;2-Amino-5-((1-((carboxymethyl)amino)-3-(methylthio)-1-oxopropan-2-yl)amino)-5-oxopentanoic acid
• CAS NO: 2922-56-7
• Molecular Formula: C11H19N3O6S
• Molecular Weight: 321.35
• Product Categories: Dipeptides and Tripeptides;Glutathione and Derivatives;Peptides
• Mol File: 2922-56-7.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 765.1°Cat760mmHg
• Flash Point: 416.5°C
• Appearance: /
• Density: 1.399g/cm³
• Vapor Pressure: 1.23E-25mmHg at 25°C
• Refractive Index: 1.565
• Storage Temp.: 2-8°C
• PKA: 2.21±0.10(Predicted)
• CAS DataBase Reference: S-METHYLGLUTATHIONE(CAS DataBase Reference)
• NIST Chemistry Reference: S-METHYLGLUTATHIONE(2922-56-7)
• EPA Substance Registry System: S-METHYLGLUTATHIONE(2922-56-7)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 2922-56-7(Hazardous Substances Data)

Usage

Uses

S-methylglutathione is a methionine containing peptide and glyoxylase inhibitor.

Biochem/physiol Actions

S-methylglutathione is a methionine containing peptide and glyoxylase inhibitor.

InChI:InChI=1/C11H19N3O6S/c1-21-5-7(10(18)13-4-9(16)17)14-8(15)3-2-6(12)11(19)20/h6-7H,2-5,12H2,1H3,(H,13,18)(H,14,15)(H,16,17)(H,19,20)/t6-,7-/m0/s1

Upstream product

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Relevant articles and documents

Partial Methanolysis and Fast Atom Bombardment Mass Spectrometry of Peptides Containing Sulphurated Amino Acids

Sequence determination by partial methanolysis and fast atom bombardment (FAB) mass spectrometry of peptides containing cysteine and methionine was investigated.Cysteine-containing peptides require methylation of the sulphydryl group by methyl iodide to give a stable S-methylcysteinyl residue prior to partial methanolysis and mass spectrometry.Methionine-containing peptides undergo partially a methylation on sulphur during methanolysis, with formation of an S-methylsulphonium ion which under FAB conditions is extracted from the matrix and eliminates methyl sulphide in the gas phase.The presence of additional peaks due to chemical modifications or gas-phase fragmentations, however, does not interfere with sequence information of the spectra.

PROPHYLACTIC OR THERAPEUTIC AGENT FOR DIARRHEA

A compound having calcium-receptor activation action can be used as an active ingredient of a prophylactic or therapeutic agent for diarrhea. The compound including a peptide such as γ-Glu-X-Gly (X represents an amino acid or an amino acid derivative), γ-

CALCIUM RECEPTOR ACTIVATOR

A calcium receptor activator containing one or more kinds of substances selected from á-Glu-Cys-Gly, á-Glu-Cys(SNO)-Gly, á-Glu-Ala, á-Glu-Gly, á-Glu-Cys, á-Glu-Met, á-Glu-Thr, á-Glu-Val, á-Glu-Orn, Asp-Gly, Cys-Gly, Cys-Met, Glu-Cys, Gly-Cys, Leu-Asp, D-Cys, á-Glu-Met(O), á-Glu-Val-Val, á-Glu-Val-Glu, á-Glu-Val-Lys, á-Glu- á-Glu-Val, á-Glu-Val-NH2, á-Glu-Val-ol, á-Glu-Ser, á-Glu-Tau, á-Glu-Cys(S-Me)(O), á-Glu-Leu, á-Glu-Ile, á-Glu-t-Leu, á-Glu-Cys(S-allyl)-Gly, á-Glu-Gly-Gly, á-Glu-Val-Phe, á-Glu-Val-Ser, á-Glu-Val-Pro, á-Glu-Val-Arg, á-Glu-Val-Asp, á-Glu-Val-Met, á-Glu-Val-Thr, á-Glu-Val-His, á-Glu-Val-Asn,á-Glu-Val-Gln, á-Glu-Val-Cys, á-Glu-Val-Orn, á-Glu-Ser-Gly, á-Glu-Cys(S-Me), á-Glu-Abu-Gly, á-Glu-Cys(S-Me)-Gly, and á-Glu-Val-Gly.