2937-83-9

Basic information

• Product Name: 1-PIPERIDINEPENTANOL
• Synonyms: 1-(5-HYDROXYPENTYL)PIPERIDINE;1-PIPERIDINEPENTANOL;5-(piperidin-1-yl)pentan-1-ol;5-(1-Piperidinyl)-1-pentanol;5-Piperidino-1-pentanol
• CAS NO: 2937-83-9
• Molecular Formula: C₁₀H₂₁NO
• Molecular Weight: 171.28
• Mol File: 2937-83-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 140 °C / 13mmHg
• Flash Point: 107.5 °C
• Appearance: /
• Density: 0.94
• Vapor Pressure: 0.00151mmHg at 25°C
• Refractive Index: 1.4710-1.4810
• PKA: 15.18±0.10(Predicted)
• CAS DataBase Reference: 1-PIPERIDINEPENTANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PIPERIDINEPENTANOL(2937-83-9)
• EPA Substance Registry System: 1-PIPERIDINEPENTANOL(2937-83-9)

Safety Data

• Hazard Codes: N
• Statements: 51/53
• Safety Statements: 61
• HazardClass: IRRITANT
• Hazardous Substances Data: 2937-83-9(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 30, p. 2450, 1965 DOI: 10.1021/jo01018a501

InChI:InChI=1/C10H21NO/c12-10-6-2-5-9-11-7-3-1-4-8-11/h12H,1-10H2

Upstream product

• 95650-50-3 5-(1-Oxy-piperidin-1-yl)-pentan-1-ol 

Downstream Products

• 259525-01-4 4-(4-fluorophenyl)-2-methyl-6-(5-piperidinopentyloxy)pyrimidine 
• 178429-96-4 4-(4-Fluorophenoxy)-2-methyl-6-(5-piperidinopentyloxy)pyrimidine hydrochloride 
• 178429-67-9 4-(4-fluorophenyl)-2-methyl-6-(5-piperidinopentyloxy)pyrimidine hydrochloride 

Relevant articles and documents

EVOLUTION THERMIQUE DE N-OXYDES D'ω-DIALKYLAMINO ALCANOLS-1

The thermolysis of ω-dimethylamino-1-alkanol N-oxides affords ω-hydroxy-1-alkenes with dimethylhydroxylamine in good yields.The other basic products (amino alcohol and isoxazolidine) involve oxidation-reduction process between the tertiary amine N-oxide and dimethylhydroxylamine, followed by 1,3-dipolar cycloaddition reaction.Pyrolysis of 5-piperidino-1-pentanol N-oxide proceeds on a path similar to the N-dimethyl compounds.The elimination of an hydrogen atom of the heterocycle does not occur: the preferred planar transition state cannot be attained because of thesteric requirements of the ring.