2999-40-8

Basic information

• Product Name: PHLOROGLUCINOL TRIACETATE
• Synonyms: 1,3,5-TRIACETOXYBENZENE;PHOLOROGLUCINOL TRIACETATE;PHLOROGLUCINOL TRIACETATE;(3,5-diacetyloxyphenyl) acetate;(3,5-diacetyloxyphenyl) ethanoate;acetic acid (3,5-diacetoxyphenyl) ester
• CAS NO: 2999-40-8
• Molecular Formula: C₁₂H₁₂O₆
• Molecular Weight: 252.22
• Product Categories: Aromatic Esters
• Mol File: 2999-40-8.mol
• Article Data: 30

Chemical Properties

• Melting Point: 104-105ºC
• Boiling Point: 348.7 ºC at 760 mmHg
• Flash Point: 153.4 ºC
• Appearance: /
• Density: 1.246 g/cm³
• CAS DataBase Reference: PHLOROGLUCINOL TRIACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: PHLOROGLUCINOL TRIACETATE(2999-40-8)
• EPA Substance Registry System: PHLOROGLUCINOL TRIACETATE(2999-40-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 2999-40-8(Hazardous Substances Data)

Usage

General Description

Phloroglucinol triacetate is a chemical compound that is derived from phloroglucinol, a polyphenol found in plants such as certain fruiting bodies and in some species of oak. Phloroglucinol triacetate is most commonly used as a pharmaceutical intermediate, particularly in the production of antispasmodic drugs. It functions as a reducing agent and has the ability to protect against oxidative stress. Additionally, it has potential applications in the synthesis of fragrances, dyes, and other organic compounds. Due to its versatile chemical reactivity and pharmacological properties, phloroglucinol triacetate is an important and valuable compound in the field of medicinal chemistry and organic synthesis.

Upstream product

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• 117-39-5 quercetol 
• 108-24-7 acetic anhydride 
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• 108-22-5 Isopropenyl acetate 
• 621-23-8 1,2,3-trimethoxybenzene 
• 64-19-7 acetic acid 
• 89475-38-7 2,3',4,4',6-Pentaacetoxy-chalkon 
• 528-58-5 cyanidin chloride 
• 480-40-0 5,7-dihydroxy-2-phenyl-chromen-4-one 
• 75-36-5 acetyl chloride 
• 127-09-3 sodium acetate 

Downstream Products

• 2161-87-7 1,3,5-triacetyl-2,4,6-trihydroxybenzene 
• 2161-86-6 2,4-diacetylphloroglucinol 
• 4328-17-0 trinitrophloroglucinol 
• 59434-20-7 1,3,5-tri-O-benzylphloroglucinol 
• 621-23-8 1,2,3-trimethoxybenzene 
• 116345-96-1 5-hydroxy-1,3-phenylene diacetate 
• 850399-67-6 1,3-di-O-acetyl-5-O-benzyl-benzophenone 
• 108-73-6 3,5-dihydroxyphenol 
• 133649-23-7 <(15)N3>Trinitrophloroglucinol 
• 17820-33-6 acetic acid 5-acetoxy-2-acetyl-3-hydroxyphenyl ester 
• 104654-31-1 5-acetoxy-2,4-diacetyl-1,3-dihydroxybenzene 
• 124607-18-7 5,7-dihydroxy-4-(4-hydroxyphenyl)-2H-1-benzopyran-2-one 
• 97776-01-7 5,7-dihydroxy-4'-benzyloxy-4-phenylcoumarin 
• 59291-87-1 1-benzyloxy-3,5-dihydroxybenzene 

Relevant articles and documents

COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF AS INHIBITORS OF RAN GTPASE

Compounds of general formula IA, IB and IC outlined below, including pharmaceutically acceptable salts, solvates and hydrates thereof. Such compounds and pharmaceutical compositions comprising them may be used in medical conditions involving Ran GTPase.

Protection of COOH and OH groups in acid, base and salt free reactions

We report an iron-catalyzed general functional group protection method with inexpensive reagents. This environmentally benign process does not use acids or bases, and does not produce waste products. Further purification beyond filtration and evaporation is, in most cases, unnecessary. Free COOH and OH groups can be protected in a one-pot reaction.

Synthesis and antibacterial activity of new symmetric polyoxygenated dibenzofurans

A series of symmetric polyoxygenated dibenzofurans with 2-methylbutyril moieties at C-4 and C-6 were obtained from commercial phloroglucinol through a sequence of reactions that include monoacylation, iodination, Suzuki-Miyaura coupling, oxidative dimeriz