30062-34-1Relevant articles and documents
Synthesis, opto-physics, and electroluminescence of cyclometalated iridium (III) complex with alkyltrifluorene picolinic acid
Wang, Yafei,Tan, Hua,Liu, Yu,Jiang, Chenxian,Hu, Zhengyong,Zhu, Meixiang,Wang, Lei,Zhu, Weiguo,Cao, Yong
, p. 1483 - 1488 (2010)
To improve the opto-physics, electroluminescence, and dispersibility of iridium (III) complexes in polymer light-emitting devices, we synthesized and characterized two red-emitting heteroleptic cyclometalated iridium (III) complexes of (Piq)2Ir(Tfl-pic) and (Piq)2Ir(Brfl-pic), in which Piq is 1-phenylisoquinoline, Tfl-pic and Brfl-pic are alkyltrifluorene- and dibromoalkylfluorene-containing picolinic acid derivatives bridged with alkoxy chain, respectively. Compared to (Piq)2Ir(pic) and (Piq)2Ir(Brfl-pic), (Piq)2Ir(Tfl-pic) exhibited higher thermal stability, better dispersibility and excellent quantum efficiency. High-efficiency red emission with a maximum current efficiency of 6.28 cdA-1 and a maximum EL peak at 608 nm was obtained in the (Piq)2Ir(Tfl-pic)-doped devices using a blend of poly(9,9-dioctylfluorene) and 2-(4-biphenyl)-5-(4-tert -butylphenyl)-1,3,4-oxadiazole as a host matrix.
A multi-functional picolinohydrazide-based chemosensor for colorimetric detection of iron and dual responsive detection of hypochlorite
Kim, Cheal,Kim, Mingeun,Lee, Su Chan,Lim, Mi Hee,Yang, Minuk
, (2021)
A novel effective chemosensor HPHN, (E)-6-hydroxy-N′-((2-hydroxynaphthalen-1-yl)methylene) picolinohydrazide, was synthesized. HPHN sensed Fe3+/2+ with the changes of color from yellow to orange without obvious inhibition from other cations. In addition, HPHN could detect ClO? by both the color change from yellow to colorless and the fluorescence quenching. The binding modes of HPHN with Fe3+/2+ and ClO? were determined to be 1:1 with Job plot and ESI-mass analysis. HPHN displayed low detection limits of 0.29 μM for Fe3+ and 0.77 μM for Fe2+. For ClO?, the detection limit was 6.20 μM by colorimetric method and 3.99 μM by fluorescent one, respectively. Moreover, HPHN can be employed to quantify Fe3+ and ClO? in environmental samples and apply to cell imaging for ClO?.
KIF18A INHIBITORS
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Paragraph 0276, (2020/07/14)
Compounds of formula (I): (I), as defined herein, and synthetic intermediates thereof, which are capable of modulating KIF18A protein thereby influencing the process of cell cycle and cell proliferation to treat cancer and cancer-related diseases. The invention also includes pharmaceutical compositions, including the compounds, and methods of treating disease states related to the activity of KIF18A.