301352-10-3

Basic information

• Product Name: {(1R,2R)-1-[[(3aR,4R,6R,6aR)-6-(6-Benzoylamino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethoxy]-(2-cyano-ethoxy)-phosphoryloxymethyl]-2-tert-butoxy-propyl}-carbamic acid 9H-fluoren-9-ylmethyl ester
• CAS NO: 301352-10-3
• Molecular Weight: 909.933
• Mol File: 301352-10-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {(1R,2R)-1-[[(3aR,4R,6R,6aR)-6-(6-Benzoylamino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethoxy]-(2-cyano-ethoxy)-phosphoryloxymethyl]-2-tert-butoxy-propyl}-carbamic acid 9H-fluoren-9-ylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {(1R,2R)-1-[[(3aR,4R,6R,6aR)-6-(6-Benzoylamino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethoxy]-(2-cyano-ethoxy)-phosphoryloxymethyl]-2-tert-butoxy-propyl}-carbamic acid 9H-fluoren-9-ylmethyl ester(301352-10-3)
• EPA Substance Registry System: {(1R,2R)-1-[[(3aR,4R,6R,6aR)-6-(6-Benzoylamino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethoxy]-(2-cyano-ethoxy)-phosphoryloxymethyl]-2-tert-butoxy-propyl}-carbamic acid 9H-fluoren-9-ylmethyl ester(301352-10-3)

Safety Data

• Hazardous Substances Data: 301352-10-3(Hazardous Substances Data)

Upstream product

• 189337-28-8 Fmoc-Thr(t-Bu)-ol 

Relevant articles and documents

Aminoalkyl adenylate and aminoacyl sulfamate intermediate analogues differing greatly in affinity for their cognate Staphylococcus aureus aminoacyl tRNA synthetases

Aminoalkyl adenylates and aminoacyl sulfamates derived from arginine, histidine and threonine, have been prepared and tested as inhibitors of their cognate Staphylococcus aureus aminoacyl tRNA synthetases. The arginyl derivatives were both potent nanomolar inhibitors of the Class I arginyl tRNA synthetase whereas for the Class II histidyl and threonyl tRNA synthetases, the acyl sulfamates were potent inhibitors but the adenylates had very little affinity. (C) 2000 Elsevier Science Ltd. All rights reserved.