30186-39-1

Basic information

• Product Name: 1-PHENYL-1H-PYRROLE-2-CARBALDEHYDE
• Synonyms: 1-PHENYL-1H-PYRROLE-2-CARBALDEHYDE;PHENYLPYRROLE-2-CARBOXALDEHYDE NSUBSTITUTED;1H-PYRROLE-2-CARBOXALDEHYDE, 1-PHENYL-;1-PHENYL-1H-PYRROLE-2-CARBOXALDEHYDE;1-phenyl-1H-pyrrole-2-carbaldehyde(SALTDATA: FREE);l-phenylpyrrole-2-carbaldehyde
• CAS NO: 30186-39-1
• Molecular Formula: C₁₁H₉NO
• Molecular Weight: 171.2
• Mol File: 30186-39-1.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 309.1°C at 760 mmHg
• Flash Point: 140.8°C
• Appearance: /
• Density: 1.06g/cm³
• Vapor Pressure: 0.000651mmHg at 25°C
• Refractive Index: 1.573
• CAS DataBase Reference: 1-PHENYL-1H-PYRROLE-2-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PHENYL-1H-PYRROLE-2-CARBALDEHYDE(30186-39-1)
• EPA Substance Registry System: 1-PHENYL-1H-PYRROLE-2-CARBALDEHYDE(30186-39-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26
• Hazardous Substances Data: 30186-39-1(Hazardous Substances Data)

Usage

Physical appearance

Yellowish-orange solid The compound appears as a yellowish-orange solid substance.

Strong, distinct odor

1-PHENYL-1H-PYRROLE-2-CARBALDEHYDE has a noticeable and intense smell.

Use as an intermediate

Synthesis of pharmaceuticals and other organic compounds The compound is commonly used as an intermediate in the production of various pharmaceuticals and other organic compounds.

Use as a flavoring agent

Flavoring purposes It is also utilized as a flavoring agent in food products.

Use in fragrance production

Production of fragrances 1-PHENYL-1H-PYRROLE-2-CARBALDEHYDE is employed in the creation of fragrances due to its unique odor.

Chemical classification

Aldehyde The compound is classified as an aldehyde, which is a type of organic compound containing a carbonyl group (C=O) bonded to a hydrogen atom.

Reactivity

Ability to undergo various chemical reactions 1-PHENYL-1H-PYRROLE-2-CARBALDEHYDE is known for its reactivity and can participate in a wide range of chemical reactions.

Potential health hazards

Caution required for handling Due to its potential health risks, it is important to handle this compound with care.

Flammability

Fire risk The compound is flammable, which presents an additional safety concern when handling and storing it.

InChI:InChI=1/C11H9NO/c13-9-11-7-4-8-12(11)10-5-2-1-3-6-10/h1-9H

Upstream product

• 59906-91-1 2,5-dihydro-2,5-dimethoxy-2-furaldehyde dimethyl acetal 
• 62-53-3 aniline 
• 635-90-5 1-phenylpyrrole 
• 93-61-8 N-methyl-N-phenylformamide 
• 52008-97-6 N-isopropyl-N-phenylformamide 
• 607-00-1 diphenylformamide 
• 2700-30-3 N,N-diisorpopylformamide 
• 4497-57-8 2,2,4-trimethyl-3,4-dihydroquinoline-1(2H)-carbaldehyde 
• 67-68-5 dimethyl sulfoxide 
• 1003-29-8 2-pyrrole aldehyde 
• 591-50-4 iodobenzene 
• 98-80-6 phenylboronic acid 
• 68-12-2 N,N-dimethyl-formamide 
• 20432-40-0 (E)-penta-2,4-dienal 

Downstream Products

• 174415-44-2 (E)-2-nitro-1-(N-phenylpyrrol-2-yl)prop-2-ene 
• 174415-38-4 ethyl 3-(N-phenylpyrrol-2-yl)-4,5-dihydro-1H-pyrroline-2,4-dicarboxylate 
• 174415-35-1 ethyl (E)-3-(N-phenylpyrrol-2-yl)prop-2-enecarboxaldehyde 
• 604809-97-4 ethyl (2Z)-2-methyl-3-[1-phenylpyrrol-2-yl]prop-2-enoate 
• 74809-37-3 dimethyl 1-phenyl-6,7-dihydroindole-4,5-dicarboxylate 
• 74809-39-5 dimethyl 1-phenylindole-4,5-dicarboxylate 
• 234-95-7 pyrrolo[1,2-a]quinoxaline 
• 1428368-57-3 5,6-diphenylpyrrolo[1,2-a]quinoline-9-carbaldehyde 
• 50691-32-2 2-methyl-1-phenyl-1H-pyrrole 
• 1161408-53-2 3-(naphthalen-1-yl-methyl)-6-(1-phenyl-pyrrol-2-yl)-5,6-dihydro-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole 
• 1161408-50-9 3-(4-(N,N-dimethylamino)phenyl)-6-(1-phenyl-pyrrol-2-yl)-5,6-dihydro-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole 
• 1161408-51-0 3-(2-(N-methylamino)phenyl)-6-(1-phenyl-pyrrol-2-yl)-5,6-dihydro-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole 
• 74809-24-8 dimethyl 1-phenylindole-4,7-dicarboxylate 
• 74809-29-3 1-phenyl-4,5,6,7-tetrahydroindole-cis-4,5-dicarboxylic anhydride 

Relevant articles and documents

Propionic Acid Derivatives and Methods of Use Thereof

Provided herein are compounds and pharmaceutical compositions of formula I where R1, R2, R3, R4, R5 and R6 are as described herein. Also provided pharmaceutically acceptable salts or stereoisomers of these compounds. In addition methods are provided for inhibiting the binding of an integrin to treat various pathophysiological conditions.

Selective and Efficient Formylation of Indoles (C3) and Pyrroles (C2) Using 2,4,6-Trichloro-1,3,5-Triazine/Dimethylformamide (TCT/DMF) Mixed Reagent

This study introduces an efficient method for the selective formylation of indoles and pyrroles at the positions of C(3) and C(2), respectively. The mixture of three equivalents of N,N-dimethylformamide and one equivalent of 2,4,6-trichloro-1,3,5-triazine (cyanuric chloride) generates an easy handling formylating agent for the efficient formylation of these classes of compounds to give the corresponding aldehydes under mild reaction conditions. This procedure was highly efficient, and a range of formylated indoles and pyrroles were obtained in good to excellent yields.

Copper-catalyzed aerobic methyl/methylene oxygenation and C-H formylation with a DABCO-DMSO system for the synthesis of carbonyl indoles and pyrroles

Copper-catalyzed aerobic methyl/methylene oxygenation of substituted indoles and pyrroles was developed using 1,4-diazabicyclo[2.2.2]octane (DABCO) as an additive in dimethyl sulfoxide (DMSO). Similar aerobic catalytic conditions could also be utilized for direct C-H formylation of C(3) on indoles and C(2) on pyrroles.