30216-47-8

Basic information

• Product Name: 2-(3-BROMOPHENYL)THIAZOLE
• Synonyms: 2-(3-BROMOPHENYL)THIAZOLE
• CAS NO: 30216-47-8
• Molecular Formula: C₉H₆BrNS
• Molecular Weight: 240.12
• Mol File: 30216-47-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 337.1±44.0 °C(Predicted)
• Appearance: /
• Density: 1.563±0.06 g/cm3(Predicted)
• PKA: 2.14±0.10(Predicted)
• CAS DataBase Reference: 2-(3-BROMOPHENYL)THIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-BROMOPHENYL)THIAZOLE(30216-47-8)
• EPA Substance Registry System: 2-(3-BROMOPHENYL)THIAZOLE(30216-47-8)

Safety Data

• Hazardous Substances Data: 30216-47-8(Hazardous Substances Data)

Usage

Type of compound

Heterocyclic (thiazole family)

Contains

Sulfur and nitrogen atoms

Used in

Organic synthesis and pharmaceutical research

Potential

Building block for creating new compounds or starting material for synthesis of biologically active molecules

Applications

Materials science, development of new functional materials

Safety measures

Handle and use with proper precautions to prevent exposure and reduce potential hazards.

Upstream product

• 2227-62-5 3-bromothiobenzamide 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 
• 15873-56-0 monochloroacetaldehyde hydrate 
• 591-18-4 1-Bromo-3-iodobenzene 
• 121359-48-6 2-(tri-n-butylstannyl)thiazole 
• 6952-59-6 3-cyanobromobenzene 
• 107-20-0 2-chloroethanal 

Downstream Products

• 1613642-78-6 C₃₁H₃₇N₃O₄S 
• 1654736-81-8 C₁₁H₇NS 

Relevant articles and documents

STK4 INHIBITORS FOR TREATMENT OF HEMATOLOGIC MALIGNANCIES

The application relates to compounds of Formula (I'): which modulate the activity of a kinase (e.g., STK4), a pharmaceutical composition comprising the compound, and a method of treating or preventing a disease or disorder associated with the modulation of a kinase, such as STK4.

Synthesis and structure-activity relationship studies of 3-biaryl-8-oxabicyclo[3.2.1]octane-2-carboxylic acid methyl esters

Stille cross coupling protocols were utilized for the synthesis of 3-(biaryl)-8-oxabicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl esters, which furnished products in high yields where in some cases Suzuki coupling under the conditions utilized provided complex reaction mixture. Samarium iodide reduction of the resulting coupling products produced both of the 2β-carbomethoxy-3- biaryl-8-oxabicyclo[3.2.1]octane diastereomers and the 2α-carbomethoxy-3- biaryl-8-oxabicyclo[3.2.1]octane diastereomers. Among the series synthesized, the benzothiophene substituted compounds demonstrated significant binding profiles of inhibition of WIN 35,438 with 177-fold selectivity for DAT versus SERT.