302776-68-7 Usage
Description
Diethylamino hydroxybenzoyl hexyl benzoate is an organic compound belonging to the class of benzophenones, commercially used as UVA filter and is anticipated to provide reliable protection against free radicals and premature skin aging, mainly caused by shortwave UVA radiations.
Uses
Different sources of media describe the Uses of 302776-68-7 differently. You can refer to the following data:
1. Diethylamino hydroxybenzoyl hexyl benzoate is a UV filter with high absorption in the UV-A range. Minimizing the overexposure of human skin to ultraviolet radiation that may lead to acute and chronic photodamage, diethylamino hydroxybenzoyl hexyl benzoate is an oil-soluble UV filter that may be incorporated in the oil phase of emulsions. Diethylamino hydroxybenzoyl hexyl benzoate was approved in Europe in 2005, and is also marketed in the U.S., South America, Mexico, Japan and Taiwan. It has a chemical structure similar to the classical benxophoenone drug class, and displays good photostability. It is used in concentrations up to 10% in sunscreen products, either alone or in combination with other UV absorbers.
2. Uvinul A Plus is a component of cosmetic emulsion with UV protection.
Application
Hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate may be used as a test material in investigating the structural elucidation of its transformation products in chlorinated water using liquid chromatography coupled to mass spectrometry.
Flammability and Explosibility
Nonflammable
Synthesis
Expose
3 mL of a 0.018 mg/mL solution of 3-diethylaminophenyl
2-hexanoxycarbonylbenzoate in methanol to UV-B radiation in a Luzchem
LZC-4 photoreactor equipped with 16 broad band UV-B lamps (LES-UVB-01)
at 35 °C to obtain Diethylamino hydroxybenzoyl hexyl benzoate.
in vitro
Diethylamino hydroxybenzoyl hexyl benzoate (DHHB) absorbs UV-A radiation with a peak at 354 nm. The molar absorption coefficient of Diethylamino hydroxybenzoyl hexyl benzoate in EtOH at 25°C is obtained to be 39 000 mol/dm 3 /cm at 354 nm. The emission spectrum of Diethylamino hydroxybenzoyl hexyl benzoate in EtOH is dependent on the excitation wavelength.
Check Digit Verification of cas no
The CAS Registry Mumber 302776-68-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,2,7,7 and 6 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 302776-68:
(8*3)+(7*0)+(6*2)+(5*7)+(4*7)+(3*6)+(2*6)+(1*8)=137
137 % 10 = 7
So 302776-68-7 is a valid CAS Registry Number.
InChI:InChI=1/C24H31NO4/c1-4-7-8-11-16-29-24(28)20-13-10-9-12-19(20)23(27)21-15-14-18(17-22(21)26)25(5-2)6-3/h9-10,12-15,17,26H,4-8,11,16H2,1-3H3
302776-68-7Relevant articles and documents
Synthesis method of ultraviolet absorber UVA Plus
-
Paragraph 0026; 0033; 0036-0041; 0044-0046; 0049-0050, (2020/08/22)
The invention discloses a synthesis method of an ultraviolet absorber UVA Plus. The method comprises the following steps: step 1, carrying out esterification reaction on phthalic anhydride and n-hexanol to obtain an intermediate monohexyl phthalate without other solvents, enabling the yield to reach over 99%, and enabling the intermediate to be directly subjected to the next step of reaction without refining; step 2, performing an acylation reaction on 3-hydroxy-N, N-diethylaniline and the intermediate monohexyl phthalate under the catalysis of a composite catalyst to prepare an ultraviolet absorber UVA Plus product, enabling the yield to be over 90%. The synthesis method has the advantages of easily available raw materials, easy refining and purification of the product, high yield, low production cost, and suitableness for industrial production.
COSMETIC COMPOSITIONS COMPRISING AN ESTER DERIVED FROM 4-CARBOXY-2-PYRROLIDINONE AND A MEROCYANIN SCREENING AGENT; USE OF SAID DERIVATIVE AS A SOLVENT FOR A MEROCYANIN SCREENING AGENT
-
, (2012/11/07)
The present invention relates to a composition comprising, in a cosmetically acceptable medium, at least one ester derived from 4-carboxy-2-pyrrolidinone, of formula (I) below: in which: R1 denotes a linear or branched C1-C20 alkyl radical,R2 denotes a linear or branched C1-C20 alkyl radical that may contain a C5-C6 ring, the phenyl radical, the benzyl radical or the phenethyl radical,and at least one merocyanin-type UV screening agent. The present invention also relates to the use of at least one ester derived from 4-carboxy-2-pyrrolidinone, of formula (I), as defined above, in a composition comprising, in a cosmetically acceptable medium, at least one merocyanin-type UV screening agent, as a solvent for said merocyanin screening agent, in and/or as an agent for improving the solubility of said merocyanin screening agent in said composition or with the aim of improving the sun protection factor.
ALPHA-AMINO ACID DERIVATIVES FOR IMPROVING SOLUBILITY
-
, (2011/04/13)
The invention relates to the use of α-amino acid derivatives for improving the solubility of poorly soluble substances in water or aqueous solutions and to mixtures and preferred preparations.
