302781-98-2

Basic information

• Product Name: Desfluoro EzetiMibe
• Synonyms: Desfluoro EzetiMibe;(3R,4S)-3-[(3S)-3-(4-Fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-phenyl-2-azetidinone;1-Desfluoro EzetiMibe;EzetiMibe Desfluoro Analog;(3R,4S)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one;1-phenyl-3(R)-[3-(4-fluorophenyl) -3(S)-hydroxypropyl]-4(S)-(4-hydroxyphenyl)-2-azetidinone;2-Azetidinone, 3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-phenyl-, (3R,4S)-;Ezetimibe Desfluoroaniline Analog
• CAS NO: 302781-98-2
• Molecular Formula: C24H22FNO3
• Molecular Weight: 391.4347832
• Product Categories: Impuities;Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 302781-98-2.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 642.8±55.0 °C(Predicted)
• Appearance: /
• Density: 1.293±0.06 g/cm3(Predicted)
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 9.72±0.30(Predicted)
• Stability: Hygroscopic
• CAS DataBase Reference: Desfluoro EzetiMibe(CAS DataBase Reference)
• NIST Chemistry Reference: Desfluoro EzetiMibe(302781-98-2)
• EPA Substance Registry System: Desfluoro EzetiMibe(302781-98-2)

Safety Data

• Hazardous Substances Data: 302781-98-2(Hazardous Substances Data)

Usage

Description

Desfluoro EzetiMibe is an impurity derived from the cholesterol absorption inhibitor Ezetimibe (E975000). It is also known as Ezetimibe Desfluoroaniline Analog and is used in the pharmaceutical industry for various applications.

Uses

Used in Pharmaceutical Industry:
Desfluoro EzetiMibe is used as an impurity in the development and manufacturing of cholesterol absorption inhibitors, specifically Ezetimibe (E975000). Its presence is crucial for the production process and contributes to the overall effectiveness of the medication.
Used in Research and Development:
Desfluoro EzetiMibe is utilized as a research compound for studying the properties and effects of Ezetimibe and its analogs. This helps in understanding the mechanism of action, potential side effects, and ways to improve the drug's efficacy.
Used in Quality Control:
Desfluoro EzetiMibe is employed in the quality control process of Ezetimibe production. By monitoring the levels of this impurity, manufacturers can ensure the purity and consistency of the final product, maintaining high standards of safety and efficacy.
Used in Regulatory Compliance:
As an impurity of a pharmaceutical product, Desfluoro EzetiMibe is subject to regulatory guidelines and requirements. Its presence and control in the manufacturing process are essential for meeting the standards set by regulatory authorities, ensuring the safety and reliability of the cholesterol absorption inhibitor Ezetimibe.