30289-28-2

Basic information

• Product Name: N-METHOXY-N-METHYLCARBAMOYL CHLORIDE
• Synonyms: N-METHOXY-N-METHYLCARBAMOYL CHLORIDE;N-Methoxy-N-methylcarbamic acid chloride;N-Methoxy-N-methylcarbamoyl chloride,95%;N-Methoxy-N-methylcarbamoyl Chloride
• CAS NO: 30289-28-2
• Molecular Formula: C₃H₆ClNO₂
• Molecular Weight: 123.54
• Mol File: 30289-28-2.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 60°C/18mmHg(lit.)
• Flash Point: 19.1°C
• Appearance: Clear colorless to slightly yellow/Liquid
• Density: 1.233g/cm³
• Vapor Pressure: 26.5mmHg at 25°C
• Refractive Index: 1.442-1.444
• CAS DataBase Reference: N-METHOXY-N-METHYLCARBAMOYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-METHOXY-N-METHYLCARBAMOYL CHLORIDE(30289-28-2)
• EPA Substance Registry System: N-METHOXY-N-METHYLCARBAMOYL CHLORIDE(30289-28-2)

Safety Data

• Hazard Codes: C
• Statements: 40-34-29-20/22
• Safety Statements: 45-36/37/39-26
• RIDADR: UN 3265 8/PG II
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 30289-28-2(Hazardous Substances Data)

Usage

Chemical Properties

clear colorless to slightly yellow liquid

InChI:InChI=1/C3H6ClNO2/c1-5(7-2)3(4)6/h1-2H3

Upstream product

• 75-44-5 phosgene 
• 1117-97-1 N,0-dimethylhydroxylamine 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 116-16-5 1,1,1,3,3,3-hexachloro-propan-2-one 
• 32315-10-9 bis(trichloromethyl) carbonate 

Downstream Products

• 38064-12-9 N-methoxy-N-methyl phenyl carbamate 
• 153168-70-8 C₁₇H₁₅ClF₃N₃O₅S 
• 203442-83-5 methyl 4-(N-methoxy-N-methylcarbamoyl)benzoate 
• 52898-49-4 4,N-dimethoxy-N-methylbenzamide 
• 122334-36-5 N-methoxy-N,4-dimethylbenzamide 
• 6919-61-5 N-methoxy-N-methylbenzamide 
• 80783-99-9 N-methoxy-N-methylcinnamamide 
• 132960-13-5 N-methoxy-N-methyl-3-phenyl-2-propynamide 

Relevant articles and documents

Cross-conjugated cyclopentenone prostaglandins synthesis of Δ7-10- chloro-15-deoxy PGA1 ethyl ester

The cationic cyclopentannelation reaction provides an unconventional but highly efficient strategy for the synthesis of unsaturated prostanoids and their analogs.

SPIRO-SULFONAMIDE DERIVATIVES AS INHIBITORS OF MYELOID CELL LEUKEMIA-1 (MCL-1) PROTEIN

The disclosure is directed to compounds of Formula I (I) Pharmaceutical compositions comprising compounds of Formula I as well as methods of their use and preparation, are also described.

One-Pot Synthesis of O -Aryl Carbamates

A simple, versatile, one-pot procedure for the synthesis of substituted O-aryl carbamates has been developed, and a protocol is henceforth described. N-Substituted carbamoyl chloride is formed in situ and subsequently reacted with a substituted phenol, avoiding the direct manipulation of sensitive reactants. This procedure offers an economical and efficient route to many compounds of interest.