303162-46-1

Basic information

• Product Name: 4-[2-(2-chlorophenyl)-4-(3-methylphenyl)-1,3-thiazol-5-yl]-2-pyridylamine
• Synonyms: 4-[2-(2-chlorophenyl)-4-(3-methylphenyl)-1,3-thiazol-5-yl]-2-pyridylamine
• CAS NO: 303162-46-1
• Molecular Weight: 377.897
• Mol File: 303162-46-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-[2-(2-chlorophenyl)-4-(3-methylphenyl)-1,3-thiazol-5-yl]-2-pyridylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[2-(2-chlorophenyl)-4-(3-methylphenyl)-1,3-thiazol-5-yl]-2-pyridylamine(303162-46-1)
• EPA Substance Registry System: 4-[2-(2-chlorophenyl)-4-(3-methylphenyl)-1,3-thiazol-5-yl]-2-pyridylamine(303162-46-1)

Safety Data

• Hazardous Substances Data: 303162-46-1(Hazardous Substances Data)

Usage

Structure

contains a thiazole ring with a chlorophenyl and a 3-methylphenyl substituent, along with a pyridylamine group

Potential applications

pharmaceutical industry

Biological activities

antibacterial, antifungal, and antitumor properties

Upstream product

• 2521-24-6 4-chlorothiobenzamide 
• 15717-17-6 2-chlorothiobenzamide 

Relevant articles and documents

MEDICINAL COMPOSITIONS

The present invention relates to an agent for the prophylaxis or treatment of pain, an agent for suppressing activation of osteoclast, and an inhibitor of osteoclast formation, which contains a p38 MAP kinase inhibitor and/or a TNF-α production inhibitor.

5-PYRIDYL-1,3-AZOLE COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF

An optionally N-oxidized compound represented by the formula: wherein R1 represents hydrogen, hydrocarbon, heterocycle, amino, acyl, R2 represents an aromatic group, R3 represents hydrogen, pyridyl, aromatic hydrocarbon, X represents oxygen, optionally oxidized sulfur, Y represents a bond, an oxygen, optionally oxidized sulfur, a group represented by the formula NR4 (R4 represents hydrogen, hydrocarbon or acyl) and Z represents a bond or a divalent acyclic hydrocarbon, or a salt thereof has an excellent adenosine A3 receptor antagonistic activity and is used as an agent for preventing or treating diseases related to an adenosine A3 receptor. Furthermore, the compound (I) or a salt thereof has p38 MAP kinase inhibitory activity and TNF-α inhibitory activity and is used as an agent for preventing or treating diseases related to p38 MAP kinase and diseases related to TNF-α.