3034-55-7Relevant articles and documents
Synthesis of Brominated Thiazoles via Sequential Bromination-Debromination Methods
Uzelac, Eric J.,Rasmussen, Seth C.
, p. 5947 - 5951 (2017/06/07)
The synthesis of the full family of bromothiazoles has been revisited in order to update and optimize their production. The species reported include 2-bromothiazole, 4-bromothiazole, 5-bromothiazole, 2,4-dibromothiazole, 2,5-dibromothiazole, 4,5-dibromothiazole, and 2,4,5-tribromothiazole, the majority of which are produced via sequential bromination and debromination steps. This complete family can now be produced without the use of elemental bromine, and the presented methods have allowed the physical and NMR spectroscopic characterization of the full family to be reported for the first time.
HETEROCYCLYL-SUBSTITUTED ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS
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Page/Page column 40-41, (2008/12/05)
This invention provides cholesterol absorption inhibitors of Formula I: and the pharmaceutically acceptable salts thereof, wherein R12 is a hydroxylated alkyl group and R9 contains a heterocyclic ring. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholesterol, and for treating atherosclerosis and preventing atherosclerotic disease events.
Synthesis of Stannylthiazoles and Mixed Stannylsilylthiazoles and their Use for a Convenient Preparation of Mono- and Bis-halothiazoles
Dondoni, A.,Mastellari, A. R.,Medici, A.,Negrini, E.,Pedrini, P.
, p. 757 - 760 (2007/10/02)
Stannylthiazoles and stannyl-silylthiazoles have been prepared and employed as thiazolyl carbanion equivalents in reactions with halogens to give mono- and mixed bis-halothiazoles in good yields.