3040-49-1 Usage
Highly reactive and toxic
1-Methyl-3-nitrosourea (MNU) is a chemical compound that is highly reactive and toxic, requiring careful handling and safety precautions.
Nitrosourea derivative
MNU is a derivative of nitrosoureas, which are a class of chemicals that contain a nitroso group (-NO) and a urea group (-NH2-CO-NH-).
Potent alkylating agent
MNU is a potent alkylating agent, meaning it can add alkyl groups to DNA, RNA, and proteins in cells, leading to damage and disruption of normal cellular processes.
Mutagen and carcinogen
MNU is known to be a mutagen, which means it can cause changes in the genetic material of cells, and a carcinogen, which means it can cause cancer.
Associated with various types of cancers
Exposure to MNU has been linked to the development of various types of cancers.
Used in laboratory settings
MNU is commonly used in laboratory settings as a tool for inducing mutations in experimental organisms to study the effects of genetic alterations.
Potential as a chemotherapeutic agent
MNU has been investigated for its potential as a chemotherapeutic agent for the treatment of certain types of cancer, although its use in this capacity is limited due to its high toxicity and potential for harmful side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 3040-49-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,0,4 and 0 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 3040-49:
(6*3)+(5*0)+(4*4)+(3*0)+(2*4)+(1*9)=51
51 % 10 = 1
So 3040-49-1 is a valid CAS Registry Number.
3040-49-1Relevant articles and documents
The reaction of ethylenethiourea with nitrite and transnitrosation by N-nitrosoethylenethiourea
Yamamoto,Yamada,Tanimura
, p. 3678 - 3683 (2007/10/02)
Ethylenethiourea (ETU), a degradation and metabolic product of ethylenebisdithiocarbamate fungicides, was nitrosated by NaNO2 to form N-nitrosoethylenethiourea (NETU), ETU was nitrosated much more rapidly than morpholine and methylurea, which are easily nitrosatable compounds, and NETU formation increased with lowering of the pH. NETU was most unstable around pH 10 and was rather stable in strongly alkaline media above pH 12. The main decomposition reaction of NETU in acidic media was denitrosation. Transnitrosation by NETU to secondary amines gave high yields of nitrosamines at pH 3 and even at pH 5.
