3046-94-4

Basic information

• Product Name: 2-(N-BUTYLANILINO)ETHANOL
• Synonyms: 2-(N-BUTYLANILINO)ETHANOL;N-butyl-N-2-hydroxyethylaniline;N-butyl-N-phenylethanolamine;N-butyl-N-hydroxyethylbenzenamine;N-(2-hydroxyethyl),N-butylaniline;2-[butyl(phenyl)amino]ethanol;2-(N-BUTYLANILINO)ET;N-butyl-n-hydroxy aniline
• CAS NO: 3046-94-4
• Molecular Formula: C₁₂H₁₉NO
• Molecular Weight: 193.28536
• EINECS: 221-253-5
• Mol File: 3046-94-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 341.4 °C at 760 mmHg
• Flash Point: 124.7 °C
• Appearance: /
• Density: 1.012g/cm³
• Vapor Pressure: 0.000255mmHg at 25°C
• Refractive Index: 1.547
• Storage Temp.: 2-8°C
• PKA: 14.66±0.10(Predicted)
• CAS DataBase Reference: 2-(N-BUTYLANILINO)ETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(N-BUTYLANILINO)ETHANOL(3046-94-4)
• EPA Substance Registry System: 2-(N-BUTYLANILINO)ETHANOL(3046-94-4)

Safety Data

• Hazardous Substances Data: 3046-94-4(Hazardous Substances Data)

Usage

General Description

2-(N-Butylanilino)ethanol is a chemical compound that belongs to the class of organic compounds known as phenol ethers. These are aromatic compounds containing an ether group substituted with a benzene ring. The exact molecular structure of 2-(N-Butylanilino)ethanol is C14H21NO2 with a molar mass of 235.32 g/mol, and it appears as a powdery solid substance. This chemical is used primarily in the chemical industry as an intermediate substance or agent in the synthesis of more complex chemical compounds due to its reactivity and versatility. However, like many chemicals, it needs to be handled with care to prevent exposure, ingestion, or inhalation, which could potentially cause harm. There is insufficient data available on its environmental and health impact, making potential risks and specific regulatory compliance for this chemical uncertain.

InChI:InChI=1/C12H19NO/c1-2-3-9-13(10-11-14)12-7-5-4-6-8-12/h4-8,14H,2-3,9-11H2,1H3

Upstream product

• 109-65-9 1-bromo-butane 
• 122-98-5 2-Anilinoethanol 
• 23402-75-7 lithium di-tertbutyl cuprate 
• 87-72-9 D-Xylose 
• 1126-78-9 N-(n-butyl)aniline 
• 75-21-8 oxirane 

Downstream Products

• 100966-13-0 N-(2-ethoxy-ethyl)-N-butyl-aniline 
• 860524-23-8 4-[butyl-(2-hydroxy-ethyl)-amino]-benzaldehyde 
• 335672-90-7 trans-2-n-butyl-2-[4-({4-[(5-methylisoxazol-3-yl-amino)sulfonyl]phenyl}diazenyl)phenylamino]ethyl methacrylate 
• 335672-99-6 trans-2-n-butyl-2-[4-({4-[(1,3-thiazol-2-ylamino)sulfonyl]phenyl}diazenyl)phenylamino]ethyl methacrylate 
• 335672-84-9 N-butyl-N-[2-(methacryloyloxy)ethyl]aniline 
• 107778-81-4 N-butyl-N-(2-vinyloxy-ethyl)-aniline 
• 103649-44-1 3-{4-[butyl-(2-hydroxy-ethyl)-amino]-benzylidenamino}-benzenesulfonic acid 
• 53817-39-3 N-butyl-N-(2-chloro-ethyl)-aniline 

Relevant articles and documents

Direct hydroxyethylation of amines by carbohydrates: Via ruthenium catalysis

An efficient and halogen-free catalytic methodology for the synthesis of β-amino alcohols from aromatic amines and biomass-derived carbohydrates is demonstrated for the first time. The activation of C5/C6 sugars by a ruthenium catalyst selectively generates the C2 alkylating reagent glycolaldehyde. The transformation involves metal-catalyzed hydrogen borrowing for the reduction of the imine intermediate. A series of arylamines bearing various substituents were successfully transformed into the desired products in good to excellent yields.

Novel N-Alkylation of Amines with Organocopper Reagents

A mild and efficient method for the N-alkylation of amines is described, based on the oxidative coupling of lithium alkylcopper amide, which is derived from lithium dialkylcuprates and primary or secondary amines.The high chemospecificity of the method was demonstrated.