304696-11-5

Basic information

• Product Name: 2-(3-benzyl-ureido)-oxazole-5-carboxylic acid ethyl ester
• CAS NO: 304696-11-5
• Molecular Weight: 289.291
• Mol File: 304696-11-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(3-benzyl-ureido)-oxazole-5-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-benzyl-ureido)-oxazole-5-carboxylic acid ethyl ester(304696-11-5)
• EPA Substance Registry System: 2-(3-benzyl-ureido)-oxazole-5-carboxylic acid ethyl ester(304696-11-5)

Safety Data

• Hazardous Substances Data: 304696-11-5(Hazardous Substances Data)

Upstream product

• 113853-16-0 2-amino-oxazole-5-carboxylic acid ethyl ester 
• 3173-56-6 benzyl isothiocyanate 
• 33142-21-1 ethyl 2-chloro-3-oxopropanoate 

Downstream Products

• 304696-12-6 2-(3-benzyl-ureido)-oxazole-5-carboxylic acid 

Relevant articles and documents

Synthesis of highly potent and selective hetaryl ureas as integrin αVβ3-receptor antagonists

Solid-phase synthesis and SAR of integrin αVβ3-receptor antagonists containing a urea moiety as non-basic guanidine mimetic are described. The most potent compounds exhibited IC50 values towards αVβ3 in the nanomolar range and high selectivity versus related integrins like αIIbβ3. For selected examples efficacy in functional cellular assays is demonstrated.