30510-18-0

Basic information

• Product Name: 3-OXO-3-(3-PYRIDINYL)PROPANENITRILE
• Synonyms: 3-OXO-3-PYRIDIN-3-YL-PROPIONITRILE;3-OXO-3-(3-PYRIDINYL)PROPANENITRILE;3-Oxo-3-pyridin-3-ylpropanenitrile;Beta-oxo-3-Pyridinepropanenitrile;3-oxo-3-(yridine-3-yl)propanenitrile;b-oxo-3-Pyridinepropanenitrile;3-Pyridinepropanenitrile, .beta.-oxo-;3-Oxo-3-(3-pyridyl)propanenitrile
• CAS NO: 30510-18-0
• Molecular Formula: C₈H₆N₂O
• Molecular Weight: 146.15
• Product Categories: Pyridines
• Mol File: 30510-18-0.mol
• Article Data: 15

Chemical Properties

• Melting Point: 79-81°C
• Boiling Point: 344.254 °C at 760 mmHg
• Flash Point: 161.999 °C
• Appearance: /
• Density: 1.178 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.54
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• PKA: 6.46±0.10(Predicted)
• CAS DataBase Reference: 3-OXO-3-(3-PYRIDINYL)PROPANENITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-OXO-3-(3-PYRIDINYL)PROPANENITRILE(30510-18-0)
• EPA Substance Registry System: 3-OXO-3-(3-PYRIDINYL)PROPANENITRILE(30510-18-0)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 30510-18-0(Hazardous Substances Data)

Usage

General Description

3-OXO-3-(3-PYRIDINYL)PROPANENITRILE is a type of chemical compound having the chemical formula C9H8N2O. The structure consists of a three-carbon chain (propane) attached to a pyridine ring, a benzene ring with a nitrogen atom, and has a nitrile group (-CN) at one end and a carbonyl group (C=O) at the other end, making it a type of keto nitrile. 3-OXO-3-(3-PYRIDINYL)PROPANENITRILE’s molecular weight is 160.17 g/mol. The detailed information about its physical and chemical properties, toxicity, or applications are not readily available, which suggests it may not be widely used or studied. Its handling and use should be performed with caution until more specific information is known.

InChI:InChI=1/C8H6N2O/c9-4-3-8(11)7-2-1-5-10-6-7/h1-2,5-6H,3H2

Upstream product

• 773837-37-9 sodium cyanide 
• 6221-12-1 3-Bromoacetylpyridine 
• 59-67-6 nicotinic acid 
• 93-60-7 methyl 3-pyridinecarboxylate 
• 75-05-8 acetonitrile 
• 59846-45-6 nicotinoyl imidazolide 
• 1195-45-5 para-fluorophenyl isocyanate 
• 614-18-6 3-pyridinecarboxylic acid ethyl ester 

Downstream Products

• 149246-87-7 3-(pyridin-3-yl)-1 H-pyrazol-5-amine 
• 1401219-41-7 N-(3-(pyridin-3-yl)-1-(p-tolyl)-1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 
• 1058705-60-4 3?(pyridin?3?yl)?1?p?tolyl?1H?pyrazol?5?amine 
• 1449412-26-3 5-nicotinoyl-1-phenyl-3-(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridin-6(7H)-one 
• 1448316-75-3 N-{2,4-dimethyl-5-[6-(pyridin-3-yl)-1H-imidazo[1,2-b]pyrazol-1-yl]phenyl}-3-(2-fluoropropan-2-yl)benzamide 
• 1448316-74-2 N-{2,4-dimethyl-5-[6-(pyridin-3-yl)-1H-imidazo[1,2-b]pyrazol-1-yl]phenyl}-3-(2-hydroxypropan-2-yl)benzamide 
• 1448316-59-3 N-{2,4-dimethyl-5-[6-(pyridin-3-yl)-1H-imidazo[1,2-b]pyrazol-1-yl]phenyl}-3-[(trifluoromethyl)-sulphanyl]benzamide 

Relevant articles and documents

Synthesis of Pyrazole Compounds by Using Sonication Method

A simple method for the synthesis of pyrazoles derivatives carried out by cyclization of cyanide with hydrazine hydrate by using sonication method. All the prepared compounds were characterized by 1H, 13C NMR and IR Spectroscopy.

One-Pot Four-Component Coupling Approach to Polyheterocycles: 6 H-Furo[3,2- f]pyrrolo[1,2- d][1,4]diazepine

A novel polyheterocyclic chemical space, 6H-furo[3,2-f]pyrrolo[1,2-d][1,4]diazepine, was generated by a one-pot four-component coupling reaction where multiple bonds (three C-C, one C-O, and one C-N) were formed through a domino sequence. Two heterocyclic rings (furan and diazepine) were sequentially constructed from the monocyclic pyrrole derivative under environment-friendly reaction conditions to furnish the tricyclic fused scaffold.

Synthesis of pyrazolo[3,4-b]pyridines under microwave irradiation in multi-component reactions and their antitumor and antimicrobial activities - Part 1

An efficient one-pot synthesis in multi-component system (MRCs) for the preparation of pyrazolo[3,4-b]pyridine derivatives from the reaction of 5-amino-1-phenyl-3-(pyridin-3-yl)-1H-pyrazole with 4-anisaldehyde and p-substituted β-ketonitriles or with pyru