30529-70-5

Basic information

• Product Name: 2-Chloro-6-methylnicotinic acid
• Synonyms: 2-chloro-6-methylpyridine-3-carboxylic acid;2-Chloro-6-methylnicotinic acid 98%;2-CHLORO-6-METHYL-3-PYRIDINECARBOXYLIC ACID 99+%;2-Chloro-6-methyl-3-pyridinecarboxylic acid, 2-Chloro-6-methylnicotinic acid;2-chloro-6-methyl-1,2-dihydropyridine-3-carboxylic acid;4-Chloro-6-methylnicotinic acid;2-Chloro-6-Methylnicotinic acid, 98+%;2-Chloro-6-Methylnicotinic acid, 99+% 5GR
• CAS NO: 30529-70-5
• Molecular Formula: C₇H₆ClNO₂
• Molecular Weight: 171.58
• EINECS: 250-229-7
• Product Categories: Pyridines, Pyrimidines, Purines and Pteredines;pharmacetical;Organic acids;Pyridine series;Chloropyridines;Halopyridines;Pharm intermediate
• Mol File: 30529-70-5.mol
• Article Data: 3

Chemical Properties

• Melting Point: 162-164 °C(lit.)
• Boiling Point: 163 °C / 22mmHg
• Flash Point: 150.7 °C
• Appearance: White to yellow to beige/Crystalline Powder
• Density: 1.3246 (rough estimate)
• Vapor Pressure: 9.34E-05mmHg at 25°C
• Refractive Index: 1.5560 (estimate)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• PKA: 2.28±0.28(Predicted)
• BRN: 473070
• CAS DataBase Reference: 2-Chloro-6-methylnicotinic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-6-methylnicotinic acid(30529-70-5)
• EPA Substance Registry System: 2-Chloro-6-methylnicotinic acid(30529-70-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 30529-70-5(Hazardous Substances Data)

Usage

Chemical Properties

white to yellow crystalline powder

Uses

2-Chloro-6-methylpyridine-3-carboxylic acid (2-Chloro-6-methylnicotinic acid) may be used in the synthesis of 6-methyl-2-thiophenoxynicotinic acid, required for the preparation of europium complex for staining the nucleolus of NIH 3T3, HeLa and HDF cells.

General Description

2-Chloro-6-methylpyridine-3-carboxylic acid (2-Chloro-6-methylnicotinic acid) is a nicotinic acid derivative.

InChI:InChI=1/C7H6ClNO2/c1-4-2-3-5(7(10)11)6(8)9-4/h2-3H,1H3,(H,10,11)/p-1

Upstream product

• 38116-61-9 2-hydroxy-6-methylnicotinic acid 
• 28900-10-9 2-chloro-6-methylnicotinonitrile 

Downstream Products

• 181823-86-9 2-[(2,4-dimethoxybenzyl)thio]-6-methylpyridine-3-carboxylic acid 
• 53277-47-7 2-chloro-6-methylnicotinic acid methyl ester 
• 689150-60-5 2-Chloro-6-methylnicotinic acid benzyl ester 
• 344352-53-0 6-methyl-2-(3-methylthiophenylamino)nicotinaldehyde 
• 344352-48-3 6-methyl-2-(3-nitrophenylamino)nicotinic acid 
• 191220-24-3 3-(3-Bromobenzoyl)-2-chloro-6-ethylpyridine 
• 191220-25-4 2-chloro-3-(3-chlorobenzoyl)-6-methylpyridine 
• 686264-89-1 phenylmethanaminium 2-(benzylamino)-6-methylnicotinate 
• 676534-08-0 2-chloro-N-cyclohexyl-6-methylnicotinamide 
• 846021-26-9 2-amino-6-methyl nicotinic acid 
• 1312697-17-8 5-[5-(3,5-Bistrifluoromethylphenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-indolizine-8-carboxylic acid [(2,2,2-trifluoroethylcarbamoyl)methyl]-amide 
• 1312697-60-1 5-[5-(3,5-bistrifluoromethylphenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-indolizine-8-carboxylic acid 
• 1312697-63-4 6-[5-(3,5-bistrifluoromethylphenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-2-chloro-nicotinic acid methyl ester 
• 1312697-64-5 6-[5-(3,5-bistrifluoromethylphenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-2-prop-1-ynyl-nicotinic acid methyl ester 

Relevant articles and documents

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Herbicidal pyridopyridazinones and pyridopyridazinethiones

Pyrido[2,3-d]pyridazin-5-one and pyrido[2,3-d]pyridazin-5-thione derivatives of general formula (I): STR1 wherein R and R1 independently represent hydrogen, optionally halogenated alkyl, alkenyl or alkynyl, optionally substituted heterocycle or a group --[CR41 R42 ]n -(phenyl)-(R3)q ; R2 represents halogen, optionally halogenated alkyl, alkenyl or alkynyl, CN; --CO2 R4 ; --S(O)r R4 ; --NO2 ; --NR41 R42 ; --OH; --COR4, --S(O)r R5, --CO2 R5, --OR5 ; --CONR41 R42, --OSO2 R5, --OSO2 R6, --OCH2 R5, --N(R41)COR6, --N(R41)SO2 R5, --N(R41)SO2 R6, --SO2 NR41 R42, optionally substituted phenyl, alkoxy or haloalkoxy; X represents oxygen or sulphur; R3 represents halogen, optionally halogenated alkyl, alkenyl, alkoxy, alkynyl, --OH, --S(O)r R4, --CO2 R4, COR4, --CN, --NO2, --NR41 R42, --OR5 ; --CONR41 R42, --OSO2 R5, --OSO2 R6, --OCH2 R5, --N(R41)COR6, --N(R41)SO2 R5, --N(R41)SO2 R6 or --SO2 NR41 R42 ; R4 represents a hydrogen atom or optionally halogenated C1-6 alkyl; R41 and R42, which may be the same or different, each represents a hydrogen atom or optionally halogenated C1-4 alkyl; R5 represents a phenyl group optionally substituted by from one to five groups selected from halogen, nitro, cyano, R4 and --OR4 ; m represents zero or an integer from one to three; n represents zero, one or two; where n is two, the groups --(CR41 R42)-- may be the same or different; q represents zero or an integer from one to five; r represents zero, one or two; with the proviso that when m represents zero R and R1 do not simultaneously represent hydrogen; and agriculturally acceptable salts thereof are useful as herbicides.