30738-01-3

Basic information

• Product Name: D-Apio-α-D-furanose
• Synonyms: D-Apio-α-D-furanose
• CAS NO: 30738-01-3
• Molecular Formula: C₅H₁₀O₅
• Molecular Weight: 150.1299
• Mol File: 30738-01-3.mol
• Article Data: 71

Chemical Properties

• Boiling Point: 364.2±42.0 °C(Predicted)
• Appearance: /
• Density: 1.711±0.06 g/cm3(Predicted)
• PKA: 12.16±0.60(Predicted)
• CAS DataBase Reference: D-Apio-α-D-furanose(CAS DataBase Reference)
• NIST Chemistry Reference: D-Apio-α-D-furanose(30738-01-3)
• EPA Substance Registry System: D-Apio-α-D-furanose(30738-01-3)

Safety Data

• Hazardous Substances Data: 30738-01-3(Hazardous Substances Data)

Upstream product

• 64481-62-5 methyl D-apiofuranoside 
• 26544-34-3 apiin 
• 1022980-94-4 (7S,8R)-dihydrodehydrodiconiferyl alcohol 9-O-β-D-apiofuranosyl-(1->6)-O-β-D-glucopyranoside 
• 1192501-86-2 3-O-β-D-glucopyranosyl-(1->3)-β-D-glucopyranosyl-2β,3β,16α,23-tetrahydroxyolean-12-en-28-oic acid 28-O-α-L-rhamnopyranosyl-(1->3)-β-D-xylopyranosyl-(1->4)-α-L-rhamnopyranosyl-(1->2)-α-L-arabinopyranoside 
• 1192501-87-3 3-O-β-D-glucopyranosyl-(1->3)-β-D-glucopyranosyl-2β,3β,16α,23-tetrahydroxyolean-12-en-28-oic acid 28-O-α-L-rhamnopyranosyl-(1->3)-β-D-xylopyranosyl-(1->4)-[β-D-apiosyl-(1->3)]-α-L-rhamnopyranosyl-(1->2)-α-L-arabinopyranoside 
• 1227937-35-0 4,6-decadiyne-1-O-β-D-apiofuranosyl-(1->6)-β-D-glucopyranoside 
• 1267635-92-6 (3S,5R,6S,7E,9R)-7-megastigmene-3,6,9-triol 3-O-β-D-(2'-O-β-D-apiofuranosyl)glucopyranoside 
• 1393716-28-3 (3S,5R,6S,7E,9S)-megastigm-7-ene-3,6,9-triol 3-O-β-D-(6'-O-β-D-apiofuranosyl)glucopyranoside 
• 1393716-38-5 (3S,5R,6S,7E,9R)-megastigm-7-ene-3,6,9-triol 3-O-β-D-(6'-O-β-D-apiofuranosyl)glucopyranoside 
• 1393716-48-7 (3S,5R,6S,9S)-megastigmane-3,9-diol 3-O-β-D-(6'-O-β-D-apiofuranosyl)glucopyranoside 
• 1393716-43-2 (3S,5R,6S,9R)-megastigmane-3,9-diol 3-O-β-D-(6'-O-β-D-apiofuranosyl)glucopyranoside 
• 1612285-11-6 (4-hydroxy-3-methoxyphenyl)-ethxoyl2-O-[5-O-[(2E)-3-[(2S,3R)-2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-5-benzofuranyl]-1-oxo-2-propenyl]-β-D-apiofuranosyl]-β-D-glucopyranoside 

Downstream Products

• 10592-17-3 (3S)-2-hydroxymethylbutane-1,2,3,4-tetrol 
• 6013-71-4 N-benzylphenylhydrazone of D-apiose 

Relevant articles and documents

Chemical structures of constituents from the seeds of Cassia auriculata

Five new diterpene glycosides, auricuosides I (1), II (2), III (3), IV (4), and V (5), a new flavonol glycoside, auricuoflavonoside I (6), and a new megastigmane glycoside, auricuomegastigmane I (7), were isolated from the seeds of Cassia auriculata, together with 11 known constituents. The chemical structures of seven new constituents were characterized on the basis of chemical and physicochemical evidence. In the present study, auricuosides I (1)-V (5) were obtained from the seeds of C. auriculata. To the best of our knowledge, there is no report about the isolation of kaurenolides with hydroxy group at 14-position from plants. This finding is interesting from the perspective of chemotaxonomy and biosynthesis of kaurenolide.

Bufadienolides and ecdysteroids from the whole plants of Helleborus niger and their cytotoxicity

A new bufadienolide (1), two new bufadienolide glycosides (2 and 3), a new ecdysteroid (4), and four known compounds (5–8), were isolated from the whole plants of Helleborus niger L. (Ranunculaceae). The structures of the new compounds (1–4) were determined by spectroscopic analysis, including 2D NMR spectral data, and hydrolytic studies. Compounds 1–6 showed cytotoxicity against HL-60 human leukemia cells, A549 human lung adenocarcinoma cells, and SBC-3 human small-cell lung cancer cells, with IC50 values ranging from 0.0055 to 1.9?μM. HL-60 cells treated with either 3 or 4 showed apoptosis characteristics, such as nuclear chromatin condensation, accumulation of sub-G1 cells, and activation of caspase-3/7.

Phytochemical Study of Stem and Leaf of Clausena lansium

Clausena lansium Lour. Skeels (Rutaceae) is widely distributed in South China and has historically been used as a traditional medicine in local healthcare systems. Although the characteristic components (carbazole alkaloids and coumarins) of C. lansium have been found to possess a wide variety of biological activities, little attention has been paid toward the other components of this plant. In the current study, phytochemical analysis of isolates from a water-soluble stem and leaf extract of C. lansium led to the identification of 12 compounds, including five aromatic glycosides, four sesquiterpene glycosides, two dihydrofuranocoumarin glycosides, and one adenosine. All compounds were isolated for the first time from the genus Clausena, including a new aromatic glycoside (1), a new dihydrofuranocoumarin glycoside (6), and two new sesquiterpene glycosides (8 and 9). The phytochemical structures of the isolates were elucidated using spectroscopic analyses including NMR and MS. The existence of these compounds demonstrates the taxonomic significance of C. lansium in the genus Clausena and suggests that some glycosides from this plant probably play a role in the anticancer activity of C. lansium to some extent.