307512-33-0 Usage
General Description
5,6-DIMETHYLTHIENO[2,3-D]PYRIMIDINE-4(3H)-THIONE is a heterocyclic compound with the molecular formula C7H8N2S2. It is a type of thienopyrimidine derivative and is commonly used as an intermediate in the synthesis of pharmaceutical compounds and agrochemicals. This chemical has potential applications as a fungicide and pesticide due to its biological properties. It is also used in the development of new drug candidates to treat various diseases. 5,6-DIMETHYLTHIENO[2,3-D]PYRIMIDINE-4(3H)-THIONE is a versatile compound with a range of potential applications in the fields of medicine and agriculture.
Check Digit Verification of cas no
The CAS Registry Mumber 307512-33-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,7,5,1 and 2 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 307512-33:
(8*3)+(7*0)+(6*7)+(5*5)+(4*1)+(3*2)+(2*3)+(1*3)=110
110 % 10 = 0
So 307512-33-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H8N2S2/c1-4-5(2)12-8-6(4)7(11)9-3-10-8/h3H,1-2H3,(H,9,10,11)
307512-33-0Relevant articles and documents
Synthesis and biological evaluation of substituted (thieno[2,3-d]pyrimidin- 4-ylthio)carboxylic acids as inhibitors of human protein kinase CK2
Golub, Andriy G.,Bdzhola, Volodymyr G.,Briukhovetska, Nadiia V.,Balanda, Anatoliy O.,Kukharenko, Olexander P.,Kotey, Igor M.,Ostrynska, Olga V.,Yarmoluk, Sergiy M.
, p. 870 - 876 (2011/04/22)
A novel series of substituted (thieno[2,3-d]pyrimidin-4-ylthio)carboxylic acids has been synthesized and tested in vitro towards human protein kinase CK2. It was revealed that the most active compounds inhibiting CK2 are 3-{[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]thio}propanoic acid and 3-{[5-(4-ethoxyphenyl)thieno[2,3-d]pyrimidin-4-yl]thio}propanoic acid (IC 50 values are 0.1 μM and 0.125 μM, respectively). Structure-activity relationships of 28 tested thienopyrimidine derivatives have been studied and binding mode of this chemical class has been predicted. Evaluation of the inhibitors on seven protein kinases revealed considerable selectivity towards CK2.
