30962-69-7

Basic information

• Product Name: 2-BENZO[B]THIOPHEN-2-YL-ETHANOL
• Synonyms: 2-BENZO[B]THIOPHEN-2-YL-ETHANOL;RARECHEM AM UC 0201
• CAS NO: 30962-69-7
• Molecular Formula: C₁₀H₁₀OS
• Molecular Weight: 178.25
• Mol File: 30962-69-7.mol
• Article Data: 7

Chemical Properties

• Melting Point: 80.5 °C(Solv: benzene (71-43-2); ligroine (8032-32-4))
• Boiling Point: 327.3 °C at 760 mmHg
• Flash Point: 151.8 °C
• Appearance: /
• Density: 1.243 g/cm³
• PKA: 14.68±0.10(Predicted)
• CAS DataBase Reference: 2-BENZO[B]THIOPHEN-2-YL-ETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BENZO[B]THIOPHEN-2-YL-ETHANOL(30962-69-7)
• EPA Substance Registry System: 2-BENZO[B]THIOPHEN-2-YL-ETHANOL(30962-69-7)

Safety Data

• Hazardous Substances Data: 30962-69-7(Hazardous Substances Data)

Usage

General Description

2-BENZO[B]THIOPHEN-2-YL-ETHANOL, also known as 2-(benzo[b]thiophen-2-yl)ethanol, is a chemical compound with the molecular formula C12H12OS. It is a pale yellow liquid that is commonly used as a building block or intermediate in the synthesis of various pharmaceuticals and organic compounds. 2-BENZO[B]THIOPHEN-2-YL-ETHANOL is a thiophene derivative, which is a heterocyclic compound containing sulfur and carbon atoms in the ring structure. Its main applications include its use as a solvent, as well as in the production of drugs, pesticides, and other fine chemicals. Additionally, it has been studied for its potential pharmacological activities and therapeutic properties, making it a versatile and important compound in the field of organic chemistry and pharmaceutical research.

Upstream product

• 1072-53-3 ethyleneglycol sulfate 
• 95-15-8 Benzo[b]thiophene 
• 17890-55-0 ethyl benzo[b]thiophene-2-carboxylate 
• 6314-28-9 benzo[b]thiophene-2-carboxylic acid 
• 75-21-8 oxirane 
• 50779-55-0 benzothiophen-2-yllithium 
• 29199-11-9 2-formylthiophenol 

Downstream Products

• 40412-10-0 2-(1-benzothien-2-yl)ethyl 4-methylbenzenesulfonate 
• 4565-08-6 N-(2-benzo[b]thiophen-2-yl-ethyl)-benzamide 
• 858821-54-2 1-phenyl-3,4-dihydro-benzo[4,5]thieno[3,2-c]pyridine 
• 126312-03-6 2-(benzo[b]thiophen-2-yl)ethanamine 
• 344305-20-0 3-Bromo-2-(β-hydroxyethyl)benzothiophene 
• 7136-60-9 2-(2-chloro-ethyl)-benzo[b]thiophene 

Relevant articles and documents

Copper-Catalyzed Cascade Cyclization of Indolyl Homopropargyl Amides: Stereospecific Construction of Bridged Aza-[n.2.1] Skeletons

Catalytic cycloisomerization-initiated cascade cyclizations of terminal alkynes have received tremendous interest, and been widely used in the facile synthesis of a diverse array of valuable complex heterocycles. However, these tandem reactions have been mostly limited to noble-metal catalysis, and are initiated by an exo-cyclization pathway. Reported herein is an unprecedented copper-catalyzed endo-cyclization-initiated tandem reaction of indolyl homopropargyl amides, where copper catalyzes both the hydroamination and Friedel–Crafts alkylation process. This method allows the practical and atom-economical synthesis of valuable bridged aza-[n.2.1] skeletons (n=3–6) with wide substrate scope, and excellent diastereoselectivity and enantioselectivity by a chirality-transfer strategy. Moreover, the mechanistic rationale for this novel cascade cyclization is also strongly supported by control experiments, and is distinctively different from the related gold catalysis.

COMPOSITIONS AND IMPROVED SOFT TISSUE REPLACEMENT METHODS

The present specification discloses compositions and methods of transplanting tissue useful for treating a soft tissue condition of an individual.

Sleep inducing compounds and methods relating thereto

Compounds having the following structure (I): including stereoisomers, prodrugs, and pharmaceutically acceptable salts, esters and solvates thereof, wherein R1, R2, R3a, R3b, L1, L2 and n are as defined herein. Such compounds generally function as H1 receptor ligands, and thus have utility as sleep inducing agents. Pharmaceutical compositions containing a compound of structure (I), as well as methods relating to the use thereof, are also disclosed.