31040-15-0 Usage
General Description
6-Nitro-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine is a chemical compound with a molecular formula C6H5N7O2. It is a nitro-substituted pyridine derivative with a triazolopyridine ring system. 6-Nitro-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine is used in the synthesis of various biologically active molecules and pharmaceuticals. It has potential applications in the field of medicinal chemistry and drug development due to its ability to interact with biological targets and modulate their activity. The exact properties and biological activities of 6-Nitro-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine have not been extensively studied, but it has the potential for further exploration in the development of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 31040-15-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,0,4 and 0 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 31040-15:
(7*3)+(6*1)+(5*0)+(4*4)+(3*0)+(2*1)+(1*5)=50
50 % 10 = 0
So 31040-15-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H5N5O2/c7-6-8-5-2-1-4(11(12)13)3-10(5)9-6/h1-3H,(H2,7,9)
31040-15-0Relevant articles and documents
Oxidative cyclization of 1-(pyridin-2-yl)guanidine derivatives: A synthesis of [1,2,4]triazolo[1,5-a]pyridin-2-amines and an unexpected synthesis of [1,2,4]triazolo[4,3-a]pyridin-3-amines
Ishimoto, Kazuhisa,Nagata, Toshiaki,Murabayashi, Mika,Ikemoto, Tomomi
, p. 407 - 418 (2015/03/03)
Oxidative cyclization of 1-(pyridin-2-yl)guanidine derivatives using N-chlorosuccinimide and aqueous potassium carbonate has been investigated. Chlorination of 1-(5-nitropyridin-2-yl)guanidine by N-chlorosuccinimide in methanol followed by addition of aqueous potassium carbonate gave rise to cyclization and afforded 6-nitro-[1,2,4]triazolo[1,5-a]pyridin-2-amine in one-pot. In the course of studying the scope and limitation of the reaction, it was found that some of the examined 1-(pyridin-2-yl)guanidine derivatives gave not only the desired [1,2,4]triazolo[1,5-a]pyridin-2-amines but also unexpected [1,2,4]triazolo[4,3-a]pyridin-3-amine products. As plausible reaction mechanisms of this oxidative cyclization, diazirine formation and nitrene formation are presented.
