311764-81-5Relevant articles and documents
Synthesis of 4-Aryl-4,6-dihydropyrimido[4,5-d]pyridazine-2,5(1H,3H)-diones from Biginelli Compounds
Patra, Gopal Chandra,Bhunia, Sankar Chandra,Roy, Monoj Kumar,Pal, Sudhir Chandra
, p. 130 - 134 (2013/03/14)
Biginelli compounds 1 were first brominated at Me-C(6) with 2,4,4,6-tetrabromocyclohex-2,5-dien-1-one to give Br2CH-C(6) derivatives 2. The hydrolysis of the 6-(dibromomethyl) group of 2c to give the 6-formyl derivative 3c in the presence of an