312314-37-7

Basic information

• Product Name: 2-(benzyloxy)-5-fluorobenzaldehyde
• Synonyms: 2-(benzyloxy)-5-fluorobenzaldehyde;5-fluoro-2-phenylmethoxybenzaldehyde
• CAS NO: 312314-37-7
• Molecular Formula: C₁₄H₁₁FO₂
• Molecular Weight: 230.2343432
• Mol File: 312314-37-7.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 369.3±27.0 °C(Predicted)
• Appearance: /
• Density: 1.211±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-(benzyloxy)-5-fluorobenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(benzyloxy)-5-fluorobenzaldehyde(312314-37-7)
• EPA Substance Registry System: 2-(benzyloxy)-5-fluorobenzaldehyde(312314-37-7)

Safety Data

• Hazardous Substances Data: 312314-37-7(Hazardous Substances Data)

Usage

General Description

2-(benzyloxy)-5-fluorobenzaldehyde is a chemical compound with the molecular formula C14H11FO2. It is a white to off-white solid that is commonly used in organic synthesis and as an intermediate in the production of pharmaceuticals and other fine chemicals. 2-(benzyloxy)-5-fluorobenzaldehyde is a benzaldehyde derivative, with a fluorine atom and a benzyloxy group attached to the benzene ring. It has a strong and distinct odor and is soluble in a variety of organic solvents. Due to its versatile reactivity and functional groups, 2-(benzyloxy)-5-fluorobenzaldehyde is widely utilized in the pharmaceutical and agrochemical industries for designing and synthesizing bioactive compounds and new drug candidates.

Upstream product

• 371-41-5 4-Fluorophenol 
• 347-54-6 5-fluoro-2-hydroxybenzaldehyde 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 

Downstream Products

• 1569309-78-9 (2E,6E)-2,6-bis(2-(benzyloxy)-5-fluorobenzylidene)cyclohexanone 

Relevant articles and documents

EGFR PROTEOLYSIS TARGETING CHIMERIC MOLECULES AND ASSOCIATED METHODS OF USE

The present disclosure relates to bifunctional compounds, which find utility as modulators of receptor tyrosine kinase (RTK) proteins. In particular, the present disclosure is directed to bifunctional compounds, which contain on one end a ligand which binds to an E3 ubiquitin ligase and on the other end a moiety which binds a target protein, such that the target protein is placed in proximity to the ubiquitin ligase to effectuate ubiquitination, and therefore, degradation (and inhibition) of the target protein. The present disclosure exhibits a broad range of pharmacological activities associated with degradation/inhibition of target protein. Diseases or disorders that result from aggregation or accumulation of the target protein are treated or prevented with compounds and compositions of the present disclosure.

HEXAHYDROPYRAZINOBENZ- OR -PYRIDO-OXAZEPINES CARRYING AN OXYGEN-CONTAINING SUBSTITUENT AND USE THEREOF IN THE TREATMENT OF 5-HT2C-DEPENDENT DISORDERS

The present invention relates to compound of formula (I) (I) wherein the variables are as defined in the claims and the description. The invention further relates to a pharmaceutical composition containing such compounds, to their use as modulators, espec

Enantioselective copper-catalyzed intramolecular phenolic O-H bond insertion: Synthesis of chiral 2-carboxy dihydrobenzofurans, dihydrobenzopyrans, and tetrahydrobenzooxepines

Efficient: A copper-catalyzed enantioselective intramolecular insertion of carbenoids into phenolic O-H bonds has been developed. This method can be used for the synthesis of the title compounds in high yields and excellent enantioselectivities under mild and neutral conditions (see scheme). NaBAr F=sodium tetrakis[3,5-bis(trifluoromethyl)phenyl]borate. Copyright