3131-60-0 Usage
General Description
White crystalline powder.
Air & Water Reactions
6-AZACYTIDINE may be light and air sensitive.
Reactivity Profile
6-AZACYTIDINE is an aminoalcohol. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Fire Hazard
Flash point data for 6-AZACYTIDINE are not available. 6-AZACYTIDINE is probably combustible.
Safety Profile
Mildly toxic by intraperitonealroute. An experimental teratogen. Other experimentalreproductive effects. Mutation data reported. Whenheated to decomposition it emits toxic fumes of NOx.
Check Digit Verification of cas no
The CAS Registry Mumber 3131-60-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,1,3 and 1 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 3131-60:
(6*3)+(5*1)+(4*3)+(3*1)+(2*6)+(1*0)=50
50 % 10 = 0
So 3131-60-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H12N4O5/c9-4-1-10-12(8(16)11-4)7-6(15)5(14)3(2-13)17-7/h1,3,5-7,13-15H,2H2,(H2,9,11,16)/t3-,5+,6+,7+/m0/s1
3131-60-0Relevant articles and documents
SYNTHESIS OF N1-SUBSTITUTED 6-AZACYTOSINES AND THEIR BIOLOGICAL ACTIVITY
Alekseeva, I. V.,Pal'chikovskaya, L. I.,Shalamai, A. S.,Ognyanik, S. S.,Morgart, N. V.,Petrusha, N. A.
, p. 227 - 230 (1994)
-
6-Azacytidine - Compound with wide spectrum of antiviral activity
Alexeeva,Dyachenko,Nosach,Zhovnovataya,Rybalko,Lozitskaya,Fedchuk,Lozitsky,Gridina,Shalamay,Palchikovskaja,Povnitsa
, p. 1147 - 1152 (2007/10/03)
6-Acytidine demonstrates activity against adenoviruses types 1, 2, 5. It inhibit synthesis of viral DNA and proteins. 6-AC shows antiherpetic and antiinfluenza action during experimental infection in mice. 6-AC is prospective for drug development as an antiviral substance with a wide spectrum of activity.
