313372-34-8Relevant articles and documents
Regiospecific alkylation of 5-substituted 2-acylamino-1, 3,4-thiadiazoles
Choo, Nam Sook,Hwang, Hye Jeong,Kim, Jin-Gyu,Suh, Il-Hwan
, p. 579 - 587 (2007/10/03)
5-Substituted 2-acylamino-1,3,4-thiadiazoles (2 and 3b) are quantitatively and regiospecifically alkylated with alkyl bromide at the 3-position nitrogen (endo-products) rather than at the 2-position amide-nitrogen (exo-products) under basic conditions. Th