314-03-4

Basic information

• Product Name: pimethixene
• Synonyms: pimethixene;1-Methyl-4-(9H-thioxanthen-9-ylidene)piperidine;Calmixen;Calmixene
• CAS NO: 314-03-4
• Molecular Formula: C₁₉H₁₉NS
• Molecular Weight: 293.45
• EINECS: 206-240-4
• Mol File: 314-03-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 121°C
• Boiling Point: 439.7°Cat760mmHg
• Flash Point: 219.7°C
• Appearance: /
• Density: 1.1211 (rough estimate)
• Vapor Pressure: 6.23E-08mmHg at 25°C
• Refractive Index: 1.5300 (estimate)
• PKA: 8.83±0.20(Predicted)
• CAS DataBase Reference: pimethixene(CAS DataBase Reference)
• NIST Chemistry Reference: pimethixene(314-03-4)
• EPA Substance Registry System: pimethixene(314-03-4)

Safety Data

• Hazardous Substances Data: 314-03-4(Hazardous Substances Data)

Usage

Uses

Pimethixene is an antihistamine and anticholinergic of the thioxanthene chemical class that is used to treat hyperactivity.

InChI:InChI=1/C19H19NS/c1-20-12-10-14(11-13-20)19-15-6-2-4-8-17(15)21-18-9-5-3-7-16(18)19/h2-9H,10-13H2,1H3

Upstream product

• 3967-45-1 9-(1-methyl-piperidin-4-yl)-thioxanthen-9-ol 
• 1445-73-4 1-Methyl-4-piperidone 
• 492-22-8 thio-xanthene-9-one 
• 5570-77-4 4-chloro-1-methylpiperidine 
• 29976-53-2 N-ethoxycarbonyl-4-piperidone 
• 138248-26-7 4-(9H-thioxanthen-9-ylidene)-1-piperidinecarboxylic acid ethyl ester 

Relevant articles and documents

INSECTICIDAL TRICYCLIC DERIVATIVES

It has now been found that certain tricyclic derivatives have provided unexpected insecticidal activity. These compounds are represented by formula I: wherein R through R, inclusively, and X and Y are fully described. Compositions comprising an insecticidally effective amount of at least one compound of formula I, and optionally, an effective amount of at least one of a second compound, with at least one insecticidally compatible carrier are also disclosed; along with methods of controlling insects comprising applying said compositions to the locus where insects are present or are expected to be present.

UNUSUAL REDUCTIONS INDUCED BY FORMIC ACID

Treatment of xanthene carbinol 1a or xanthenylidene derivative 2a with refluxing formic acid unexpectedly gave dihydro compound 3a.Thioxanthene and acridine carbinols 1b and 1c and acridinylidene derivative 2c were also partially reduced when treated with formic acid.