314768-38-2Relevant articles and documents
Synthesis of 5-trichloromethyl-Δ4-1,2,4-oxadiazolines and their rearrangement into formamidine derivatives
Wagner, Gabriele,Garland, Tim
, p. 3596 - 3599 (2008/09/21)
A series of 5-trichloro-Δ4-1,2,4-oxadiazolines have been synthesised by 1,3-dipolar cycloaddition of nitrones to trichloroacetonitrile. These oxadiazolines rearrange into formamidine derivatives, via ring opening and a 1,2-aryl shift from carbo
One-pot synthesis and hydroxylaminolysis of asymmetrical acyclic nitrones
Coskun, Necdet,Parlar, Aydin
, p. 2445 - 2451 (2007/10/03)
Aromatic aldehydes 1 were reductively aminated to the corresponding secondary amines 2 using NaBH4 in methanol in good yields. Amines 2 were oxidized with H2O2-WO42- regioselectively to nitrones 3, the structures of which were easily determined by reacting them with hydroxylamine hydrochloride as well as by spectral means. The products of hydroxylaminolysis in ether proved to be the corresponding benzaldehyde oximes 4 and benzyl or methyl hydroxylamine hydrochlorides 5. Copyright Taylor & Francis, Inc.