31556-28-2 Usage
General Description
4-Thiouridine triphosphate is a modified nucleoside triphosphate that contains a sulfur atom in place of the oxygen atom in the 4-position of the uridine base. It is commonly used in biochemical and molecular biology research as a substrate for RNA polymerase, as well as a tool for studying RNA synthesis and structure. 4-thiouridine triphosphate can be incorporated into RNA molecules during transcription, allowing researchers to study the structure and function of RNA and investigate the effects of sulfur substitution on RNA stability and interactions. Additionally, 4-thiouridine triphosphate has been used in photoaffinity labeling and other biochemical assays to study RNA-protein interactions and RNA modification processes. Overall, 4-thiouridine triphosphate is a valuable chemical tool for studying RNA biology and has diverse applications in molecular biology research.
Check Digit Verification of cas no
The CAS Registry Mumber 31556-28-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,5,5 and 6 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 31556-28:
(7*3)+(6*1)+(5*5)+(4*5)+(3*6)+(2*2)+(1*8)=102
102 % 10 = 2
So 31556-28-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H15N2O14P3S/c12-6-4(3-22-27(18,19)25-28(20,21)24-26(15,16)17)23-8(7(6)13)11-2-1-5(29)10-9(11)14/h1-2,4,6-8,12-13H,3H2,(H,18,19)(H,20,21)(H,10,14,29)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1
31556-28-2Relevant articles and documents
BASE-MODIFIED RNA FOR INCREASING THE EXPRESSION OF A PROTEIN
-
, (2010/03/31)
The present application describes a base-modified RNA and the use thereof for increasing the expression of a protein and for the preparation of a pharmaceutical composition, especially a vaccine, for the treatment of tumours and cancer diseases, heart and circulatory diseases, infectious diseases, autoimmune diseases or monogenetic diseases, for example in gene therapy. The present invention further describes an in vitro transcription method, in vitro methods for increasing the expression of a protein using the base-modified RNA, and an in vivo method.
