31575-75-4

Basic information

• Product Name: 2-BENZYLOXYBROMOBENZENE
• Synonyms: 1-(BENZYLOXY)-2-BROMOBENZENE;2-BENZYLOXYBROMOBENZENE;2-BROMOPHENYL BENZYL ETHER;benzyl 2-bromophenyl ether;Benzene, 1-broMo-2-(phenylMethoxy)-;1-BroMo-2-benzyloxybenzene;2-BroMophenol Benzyl Ether;Benzyloxy-1-broMobenzene
• CAS NO: 31575-75-4
• Molecular Formula: C₁₃H₁₁BrO
• Molecular Weight: 263.13
• Product Categories: Anisoles, Alkyloxy Compounds & Phenylacetates;Bromine Compounds;alkyl bromide
• Mol File: 31575-75-4.mol
• Article Data: 56

Chemical Properties

• Boiling Point: 335.2 °C at 760 mmHg
• Flash Point: >230 °F
• Appearance: /
• Density: 1.382 g/cm³
• Vapor Pressure: 0.000236mmHg at 25°C
• Refractive Index: n20/D >1.6060(lit.)
• Solubility: Chloroform, Dichloromethane, Ethyl Acetate
• CAS DataBase Reference: 2-BENZYLOXYBROMOBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BENZYLOXYBROMOBENZENE(31575-75-4)
• EPA Substance Registry System: 2-BENZYLOXYBROMOBENZENE(31575-75-4)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 31575-75-4(Hazardous Substances Data)

Usage

Chemical Properties

Colorless Oil

Uses

2-(Benzyloxy)broMobenzene can be used in the preparation of different inhibitors.

InChI:InChI=1/C13H11BrO/c14-12-8-4-5-9-13(12)15-10-11-6-2-1-3-7-11/h1-9H,10H2

Upstream product

• 583-55-1 1-Bromo-2-iodobenzene 
• 100-51-6 benzyl alcohol 
• 1072-85-1 o-fluorobromobenzene 
• 95-56-7 2-hydroxybromobenzene 
• 100-39-0 benzyl bromide 
• 584-08-7 potassium carbonate 
• 108-95-2 phenol 
• 100-44-7 benzyl chloride 

Downstream Products

• 63613-45-6 2-Benzyloxy-β-(o-benzyloxyphenyl)-3',4,4',6-tetramethoxyhydrochalkon 
• 264906-63-0 3β-(2-Benzyloxyphenyl)-5α-cholestan-3α-ol 
• 190661-29-1 2-benzyloxyphenylboronic acid 
• 137207-86-4 7-ethoxycarbonyl-4-(2-hydroxyphenyl)-6,8-dimethyl-1(2H)-phthalazinone 
• 137207-80-8 1-(2-Benzyloxy-phenyl)-5,7-dimethyl-4-oxo-3,4-dihydro-phthalazine-6-carboxylic acid ethyl ester 
• 127898-39-9 2-((1S,2R,3R,4R)-3-Hydroxymethyl-7-oxa-bicyclo[2.2.1]hept-2-ylmethyl)-phenol 
• 127898-40-2 <1S-1α,2α,3α,4α>-<3-<<3-(hydroxymethyl)-7-oxabicyclo<2.2.1>hept-2-yl>methyl>phenoxy>acetic acid, ethyl ester 
• 127898-41-3 [2-((1S,2R,3S,4R)-3-Formyl-7-oxa-bicyclo[2.2.1]hept-2-ylmethyl)-phenoxy]-acetic acid ethyl ester 
• 127898-31-1 <1S-1α,2α,3α,4α>-<2-<<3-<<<(phenylamino)carbonyl>hydrazono>methyl>-7-oxabicyclo<2.2.1>hept-2-yl>methyl>phenoxy>acetic acid 
• 127898-30-0 C₂₅H₂₉N₃O₅ 

Relevant articles and documents

Total synthesis of 7- and 8-oxygenated pyrano[3,2-a]carbazole and pyrano[2,3-a]carbazole alkaloids via boronic acid-catalyzed annulation of the pyran ring

The boronic acid-catalyzed annulation of citral opens up a short route to oxygenated cyclized monoterpenoid pyranocarbazole alkaloids. Thus, murrayamine-D is available in only three steps and 55% overall yield from the corresponding carbazole precursor.

SULFONIMIDAMIDE COMPOUNDS AS NLRP3 MODULATORS

Described herein are compounds of Formula (I), Formula (I-A), and Formula (I-B), solvates thereof, tautomers thereof, and pharmaceutically acceptable salts of the foregoing, Further described herein are methods of inhibiting NLRP3 using said compounds, and methods of and compositions useful in treating NLRP3-dependent disorders.

Improved Synthesis of MediPhos Ligands and Their Use in the Pd-Catalyzed Enantioselective N-Allylation of Glycine Esters

A new class of chiral C2-symmetric diphosphines (MediPhos) was recently shown to give superior results in the Pd-catalyzed asymmetric N-allylation of amino acid esters. We here describe a new, improved protocol for the preparation of such ligands through bidirectional SN2-coupling of a tartrate-derived ditosylate with 6-alkyl-2-bromophenols followed by double lithiation/phosphanylation. This method gave access to a series of nine ligands with branched alkyl substituents, which were benchmarked in the enantioselective Pd-catalyzed N-allylation of tert-butyl glycinate with racemic (E)-2,8-dimethylnona-5-en-4-yl methyl carbonate (up to 95 % ee). In addition, the analogous transformation of tert-butyl glycinate with methyl (E)-nona-5-en-4-yl carbonate was optimized. The obtained allylic amines were then used in the stereoselective synthesis of the conformationally restricted proline-derived dipeptide analogs ProM-17 and ProM-21.