31686-93-8

Basic information

• Product Name: methyl 2-amino-6-methylnicotinate
• CAS NO: 31686-93-8
• Molecular Weight: 166.18
• Mol File: 31686-93-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 2-amino-6-methylnicotinate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-amino-6-methylnicotinate(31686-93-8)
• EPA Substance Registry System: methyl 2-amino-6-methylnicotinate(31686-93-8)

Safety Data

• Hazardous Substances Data: 31686-93-8(Hazardous Substances Data)

Upstream product

• 53277-47-7 2-chloro-6-methylnicotinic acid methyl ester 
• 67-56-1 methanol 
• 187543-70-0 7-methylpyrido[2,3-d][1,3]oxazine-2,4-(1H)-dione 

Downstream Products

• 76336-15-7 1,2-dihydro-4-hydroxy-7-methyl-2-oxo-1,8-naphthyridine-3-carboxylic acid ethyl ester 

Relevant articles and documents

THIOALKENEAMIDES AS TRANSKETOLASE INHIBITORS

The present invention provides thioalkeneamides of formula (I) which are useful as transketolase inhibitors: wherein R1, R2, R3, R4, R5, R6, Ra-Rd, n and ring A are as defined herein. The present invention also provides pharmaceutical compositions comprising the compounds of formula (I). The invention provides methods for inhibiting transketolase activity, reducing cellular ribose-5-phosphate levels, inhibiting nucleic acid synthesis, inhibiting cell proliferation and tumor cell growth in vitro and in vivo, stimulating apoptosis in tumor cells and treating cancer by administering a compound of formula (I) or a pharmaceutical composition thereof.