3169-71-9

Basic information

• Product Name: 2-(4-FLUOROPHENOXY)ANILINE
• Synonyms: TIMTEC-BB SBB009585;AKOS B021968;2-(4-FLUOROPHENOXY)ANILINE;ART-CHEM-BB B021968;CHEMBRDG-BB 4010416;2-(4-FLUORO-PHENOXY)-PHENYLAMINE;AKOS DM0073;UKRORGSYN-BB BBV-108304
• CAS NO: 3169-71-9
• Molecular Formula: C₁₂H₁₀FNO
• Molecular Weight: 203.21
• Mol File: 3169-71-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 288.3°C at 760 mmHg
• Flash Point: 128.2°C
• Appearance: /
• Density: 1.22g/cm³
• Vapor Pressure: 0.00235mmHg at 25°C
• Refractive Index: 1.599
• CAS DataBase Reference: 2-(4-FLUOROPHENOXY)ANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-FLUOROPHENOXY)ANILINE(3169-71-9)
• EPA Substance Registry System: 2-(4-FLUOROPHENOXY)ANILINE(3169-71-9)

Safety Data

• Hazardous Substances Data: 3169-71-9(Hazardous Substances Data)

Usage

General Description

2-(4-Fluorophenoxy)aniline is a chemical compound with the molecular formula C12H10FNO. It belongs to the class of chemicals known as anilines, which are organic compounds containing an amino group attached to a phenyl ring. The presence of the fluorophenyl group contributes to its unique chemical properties, including its relative stability, its reactivity, and its interactivity with various other chemical substances. It is generally used as a precursor or building block in a variety of synthetic organic chemistry applications, including pharmaceutical chemistry, where it is used to synthesize various potential therapeutic compounds. Despite its widespread use in laboratory and industrial settings, it should be handled with care due to its possible hazards to human health and to the environment.

InChI:InChI=1/C12H10FNO/c13-9-5-7-10(8-6-9)15-12-4-2-1-3-11(12)14/h1-8H,14H2

Upstream product

• 4475-59-6 1-(4-fluorophenoxy)-2-nitrobenzene 
• 88-73-3 2-Chloronitrobenzene 
• 1493-27-2 ortho-nitrofluorobenzene 
• 371-41-5 4-Fluorophenol 

Downstream Products

• 1316273-86-5 N-[2-(4-fluorophenoxy)phenyl]acetamide 
• 203303-06-4 1-(4-fluorophenoxy)-2-iodobenzene 
• 76840-96-5 [2-(4-Fluoro-phenoxy)-phenyl]-imidazolidin-2-ylidene-amine 
• 76839-02-6 [2-(4-Fluoro-phenoxy)-phenyl]-thiourea 
• 76838-21-6 1-Benzoyl-3-[2-(4-fluoro-phenoxy)-phenyl]-thiourea 

Relevant articles and documents

Pyrazinamide compounds, preparation method and application thereof as well as bactericide

The invention relates to the field of pesticide bactericides and discloses pyrazinamide compounds, a preparation method and an application thereof as well as a bactericide. The compounds have the structure shown in formula (I). The pyrazinamide compounds with the novel structure are designed by introducing pyrazine ring fragments in Pyradiflumid and diphenyl ether fragments with wide bioactivity,and the pyrazinamide compounds can be used as novel SDHIs (succinate dehydrogenase inhibitors) or bactericides.

Design, synthesis and antifungal activity of novel furancarboxamide derivatives

Twenty-seven novel furancarboxamide derivatives with a diphenyl ether moiety were synthesized and evaluated for their antifungal activity against Rhizoctonia solani, Botrytis cirerea, Valsa Mali and Sphaceloma ampelimum. Antifungal bioassay results indicated that most compounds had good or excellent fungicidal activities for R. solani and S. ampelimum at 20 mg L-1. Among synthesized compounds, compound 18e showed a greater inhibitory effect against S. ampelimum, with half maximal effective concentration (EC50) values of 0.020 mg L-1. This strong activity rivals currently used commercial fungicides, such as Boscalid and Carbendazim, and has great potential as a lead compound for future development of novel fungicides.

Synthesis and enantioselective hydrogenation of seven-membered cyclic imines: Substituted dibenzo[b,f][1,4]oxazepines

Highly enantioselective hydrogenation of seven-membered cyclic imines, substituted dibenzo[b,f][1,4]oxazepines, was achieved, with up to 94% ee, by using the [Ir(COD)Cl]2/(S)-Xyl-C3*-TunePhos complex as the catalyst in the presence of morpholine-HCl.