31736-73-9

Basic information

• Product Name: 4'-BROMO-3-CHLOROPROPIOPHENONE
• Synonyms: 4'-Bromo-β-chloropropiophenone;4'-Bromo-3-chloropropiophenone,97%;4'-Bromo-3-chloropropiophenone,99%;1-(4-Bromophenyl)-3-chloropropan-1-one;4-BROMO-BETA-CHLOROPROPIOPHENONE;4'-BROMO-3-CHLOROPROPIOPHENONE;1-(4-BROMOPHENYL)-3-CHLORO-1-OXOPROPANE;3-chloro-4-bromopropiophenone
• CAS NO: 31736-73-9
• Molecular Formula: C₉H₈BrClO
• Molecular Weight: 247.52
• EINECS: 250-784-5
• Product Categories: Building Blocks;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;C9;Carbonyl Compounds;Ketones
• Mol File: 31736-73-9.mol
• Article Data: 12

Chemical Properties

• Melting Point: 54-59 °C(lit.)
• Boiling Point: 333.8 °C at 760 mmHg
• Flash Point: >230 °F
• Appearance: light yellow to light brown crystalline powder
• Density: 1.5182 (rough estimate)
• Vapor Pressure: 0.016Pa at 25℃
• Refractive Index: 1.5963 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility: 36mg/L at 20℃
• BRN: 1944367
• CAS DataBase Reference: 4'-BROMO-3-CHLOROPROPIOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-BROMO-3-CHLOROPROPIOPHENONE(31736-73-9)
• EPA Substance Registry System: 4'-BROMO-3-CHLOROPROPIOPHENONE(31736-73-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• RIDADR: UN1759
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 31736-73-9(Hazardous Substances Data)

Usage

Chemical Properties

light yellow to light brown crystalline powder

General Description

4′-Bromo-3-chloropropiophenone, a halogenated propiophenone derivative, is also known as 1-(4-bromophenyl)-3-chloro-1-propanone. Its molecular geometry has been studied based on density functional theory (DFT) calculations, FTIR and FT Raman spectra.

Flammability and Explosibility

Notclassified

Upstream product

• 108-86-1 bromobenzene 
• 625-36-5 2-chloropropionyl chloride 
• 51044-13-4 4-bromobenzyl triphenylphosphonium bromide 
• 109240-30-4 1-(4-bromophenyl)cyclopropan-1-ol 
• 106-37-6 1.4-dibromobenzene 
• 161386-38-5 5-[5-fluoro-3-(4-methoxytetrahydropyran-4-yl)phenylthio]indan-1-one 

Downstream Products

• 97802-07-8 4-p-bromophenyl-1,10-phenanthroline 
• 97802-13-6 4-p-biphenylyl-7-p-bromophenyl-1,10-phenanthroline 
• 97802-11-4 4-p-bromophenyl-8-aminoquinoline 
• 97802-08-9 4,7-bis-(p-bromophenyl)-1,10-phenanthroline 
• 25574-16-7 2-(4-bromophenyl)oxetane 
• 22731-70-0 1-(4-bromophenyl)prop-2-en-1-one 

Relevant articles and documents

I2-Promoted Intramolecular Oxidative Cyclization of Butenyl Anilines: A Facile Route to Benzo[b]azepines

A metal-free approach for the synthesis of seven-membered N-heterocycles has been developed by the I2-promoted intramolecular cross-coupling/annulation of butenyl anilines. This cyclization reaction involves C?H activation and C?C bond formation and exhibits good functional group tolerance. A series of benzo[b]azepine derivatives are obtained in moderate to good yields.

NEW COMPOUNDS SUITABLE AS CATALYSTS FOR POLYMERIZATION REACTIONS

The invention relates to a compound of formula (I) and a process for synthesizing said compound. The invention further relates to the use of said compound as a catalyst, preferably for polymerization, such as, olefin polymerization. The invention also relates to the polymers produced using said catalyst and articles comprising said polymers.

Regioselective Synthesis of Carbonyl-Containing Alkyl Chlorides via Silver-Catalyzed Ring-Opening Chlorination of Cycloalkanols

A novel and regioselective approach to carbonyl-containing alkyl chlorides via silver-catalyzed ring-opening chlorination of cycloalkanols is reported. Concurrent C(sp3)-C(sp3) bond cleavage and C(sp3)-Cl bond formation efficiently occur with good yields under mild conditions, and the chlorinated products are readily transformed into other useful synthetic intermediates and drugs. The reaction features complete regioselectivity, high efficiency, and excellent practicality. (Chemical Equation Presented).