318464-23-2

Basic information

• Product Name: (3S)-3-(N-t-butoxycarbonylamino)-2-hydroxy-5-methylhexanoic Acid Methyl Ester
• Synonyms: EOS-61797;methyl(3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-5-methylhexanoate;(3S)-3-(N-t-butoxycarbonylamino)-2-hydroxy-5-methylhexanoic Acid Methyl Ester;Hexanoic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-5-methyl-, methyl ester, (3S)-
• CAS NO: 318464-23-2
• Molecular Formula: C13H25NO5
• Molecular Weight: 275.34
• Mol File: 318464-23-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 391.6±32.0 °C(Predicted)
• Appearance: /
• Density: 1.068±0.06 g/cm3(Predicted)
• PKA: 11.78±0.46(Predicted)
• CAS DataBase Reference: (3S)-3-(N-t-butoxycarbonylamino)-2-hydroxy-5-methylhexanoic Acid Methyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: (3S)-3-(N-t-butoxycarbonylamino)-2-hydroxy-5-methylhexanoic Acid Methyl Ester(318464-23-2)
• EPA Substance Registry System: (3S)-3-(N-t-butoxycarbonylamino)-2-hydroxy-5-methylhexanoic Acid Methyl Ester(318464-23-2)

Safety Data

• Hazardous Substances Data: 318464-23-2(Hazardous Substances Data)

Usage

General Description

The chemical compound (3S)-3-(N-t-butoxycarbonylamino)-2-hydroxy-5-methylhexanoic Acid Methyl Ester is a derivative of a naturally occurring amino acid. It is commonly used in the pharmaceutical industry as a building block for the synthesis of various drugs and pharmaceutical compounds. (3S)-3-(N-t-butoxycarbonylamino)-2-hydroxy-5-methylhexanoic Acid Methyl Ester contains a hydroxy group, a carboxylic acid group, and an amino group, making it a versatile intermediate in organic synthesis. Additionally, its ester functionality makes it suitable for use as a prodrug, allowing for improved delivery and absorption in the body. Overall, (3S)-3-(N-t-butoxycarbonylamino)-2-hydroxy-5-methylhexanoic Acid Methyl Ester has a range of potential applications in medicinal chemistry and drug development.

Upstream product

• 341973-08-8 (3S)-3-amino-2-hydroxy-5-methylhexanoic Acid Methyl Ester Hydrochloride 
• 34619-03-9 tert-butyldicarbonate 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 341973-08-8 (3S)-3-amino-2-hydroxy-5-methylhexanoic Acid Methyl Ester Hydrochloride 

Relevant articles and documents

DIKETOHYDRAZINE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT

The present invention relates to a diketohydrazine derivative of formula (I) and a pharmaceutically acceptable salt thereof (the symbols in the formula have the same meaning as described in the specification). The compound of formula (I) has an inhibitory activity against cysteine protease, and it is useful for the treatment of inflammatory diseases, immune diseases, ischemic diseases, respiratory diseases, circulatory diseases, blood diseases, neuronal diseases, hepatic or biliary diseases, osseous or articular diseases, metabolic diseases, etc. And the compound has inhibitory activity against elastase and it is also useful for the treatment of COPD (chronic obstacle pulmonary diseases).

1,3,4-Oxadiazoline derivatives and drugs containing these derivatives as active ingredient

A 1,3,4-oxadiazoline derivative of formula (I) , wherein W is oxygen, sulfer; R is hydrogen, alkyl, CycA, etc.; AA1 is a single bond, amino acid residue, etc.; AA2 is a single bond, amino acid residue, etc.; R7 and R8 are hydrogen, alkyl, etc.; R9 is hydrogen, alkyl, etc., and a non-toxic salt thereof. The compound of formula (I) has an inhibitory activity against cysteine protease and therefore it is useful as an agent for the prophylaxis and/or treatment of inflammatory diseases, diseases induced by apoptosis, diseases induced by disorders of immune responses, autoimmune diseases, diseases induced by decomposition of proteins which compose organism, shock, circulatory system disorders, blood coagulation systems disorders, malignant tumors, acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC), parasitic diseases, nerve degeneration diseases, pulmonary disorders, bone resorption diseases, endocrinesthenia, etc.