32122-11-5

Basic information

• Product Name: METHYL 4-BENZYLOXYBENZOATE
• Synonyms: METHYL 4-(BENZYLOXY)BENZENECARBOXYLATE;METHYL 4-BENZYLOXYBENZOATE;LABOTEST-BB LT00455680;4-BENZYLOXYBENZOIC ACID METHYL ESTER;RARECHEM AL BF 0087;METHYL 4-BENZYLOXYBENZONATE;4-Methylbenzoicacidbenzyloxygenradicals
• CAS NO: 32122-11-5
• Molecular Formula: C₁₅H₁₄O₃
• Molecular Weight: 242.27
• Product Categories: Aromatic Esters
• Mol File: 32122-11-5.mol
• Article Data: 65

Chemical Properties

• Melting Point: 99°C
• Boiling Point: 372.5°Cat760mmHg
• Flash Point: 156.2°C
• Appearance: /
• Density: 1.142g/cm³
• Vapor Pressure: 9.56E-06mmHg at 25°C
• Refractive Index: 1.566
• Solubility: soluble in Acetone
• BRN: 2119212
• CAS DataBase Reference: METHYL 4-BENZYLOXYBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 4-BENZYLOXYBENZOATE(32122-11-5)
• EPA Substance Registry System: METHYL 4-BENZYLOXYBENZOATE(32122-11-5)

Safety Data

• Safety Statements: 22-24/25
• RIDADR: 3077
• Hazardous Substances Data: 32122-11-5(Hazardous Substances Data)

Usage

Chemical Properties

White solid

InChI:InChI=1/C15H14O3/c1-17-15(16)13-7-9-14(10-8-13)18-11-12-5-3-2-4-6-12/h2-10H,11H2,1H3

Upstream product

• 100-44-7 benzyl chloride 
• 99-76-3 methyl 4-hydroxylbenzoate 
• 100-39-0 benzyl bromide 
• 133642-20-3 4-(tert-butyldimethylsilanyloxy)benzoic acid methyl ester 
• 67-56-1 methanol 
• 4397-53-9 p-benzyloxybenzaldehyde 
• 500891-82-7 benzyl 4-methoxyphenyl carbonate 
• 302569-86-4 benzyl 4-(methoxycarbonyl)phenyl carbonate 
• 13326-10-8 benzyl methyl carbonate 
• 20269-55-0 methyl-4-hydroxybenzoate anion 
• 99-96-7 4-hydroxy-benzoic acid 
• 1589-82-8 phenylmagnesium bromide 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 100-51-6 benzyl alcohol 

Downstream Products

• 836-43-1 4-benzyloxybenzyl alcohol 
• 128958-65-6 4-benzyloxyphenylhydrazide 
• 99-76-3 methyl 4-hydroxylbenzoate 
• 24262-66-6 methyl 4-acetoxybenzoate 
• 1243707-74-5 N-(6-amino-2,4-dioxo-3-propyl-1,2,3,4-tetrahydro-pyrimidin-5-yl)-4-benzyloxy-benzamide 
• 1243707-76-7 8-(4-benzyloxy-phenyl)-2-chloro-1-propyl-1,7-dihydro-purin-6-one 
• 1243707-77-8 8-(4-benzyloxy-phenyl)-2-chloro-1-propyl-7-(2-trimethylsilanyl-ethoxymethyl)-1,7-dihydro-purin-6-one 
• 1243707-79-0 8-(4-hydroxy-phenyl)-1-propyl-7-(2-trimethylsilanyl-ethoxymethyl)-1,7-dihydro-purin-6-one 
• 1243706-51-5 8-(4-hydroxy-phenyl)-1-propyl-1,7-dihydro-purin-6-one 
• 1243707-80-3 8-{4-[3-(4-fluoro-phenyl)-prop-2-ynyloxy]-phenyl}-1-propyl-7-(2-trimethylsilanyl-ethoxymethyl)-1,7-dihydro-purin-6-one 
• 1243706-52-6 8-{4-[3-(4-fluorophenyl)prop-2-ynyloxy]phenyl}-1-propyl-1,7-dihydropurin-6-one 
• 1243707-84-7 N-(4-cyano-phenyl)-2-{4-[6-oxo-1-propyl-7-(2-trimethylsilanyl-ethoxymethyl)-6,7-dihydro-1H-purin-8-yl]-phenoxy}-acetamide 
• 1243706-59-3 [4-(6-oxo-1-propyl-6,7-dihydro-1H-purin-8-yl)phenoxy]acetic acid 
• 1243707-89-2 8-(4-Benzyloxy-phenyl)-1-propyl-2-(3-trifluoromethyl-phenyl)-7-(2-trimethylsilanyl-ethoxymethyl)-1,7-dihydro-purin-6-one 

Relevant articles and documents

A “universal” catalyst for aerobic oxidations to synthesize (hetero)aromatic aldehydes, ketones, esters, acids, nitriles, and amides

Functionalized (hetero)aromatic compounds are indispensable chemicals widely used in basic and applied sciences. Among these, especially aromatic aldehydes, ketones, carboxylic acids, esters, nitriles, and amides represent valuable fine and bulk chemicals, which are used in chemical, pharmaceutical, agrochemical, and material industries. For their synthesis, catalytic aerobic oxidation of alcohols constitutes a green, sustainable, and cost-effective process, which should ideally make use of active and selective 3D metals. Here, we report the preparation of graphitic layers encapsulated in Co-nanoparticles by pyrolysis of cobalt-piperazine-tartaric acid complex on carbon as a most general oxidation catalyst. This unique material allows for the synthesis of simple, functionalized, and structurally diverse (hetero)aromatic aldehydes, ketones, carboxylic acids, esters, nitriles, and amides from alcohols in excellent yields in the presence of air.

Design and biological evaluation of phenyl imidazole analogs as hedgehog signaling pathway inhibitors

The hedgehog (Hh) signaling pathway is involved in diverse aspects of cellular events. Aberrant activation of Hh signaling pathway drives oncogenic transformation for a wide range of cancers, and it is therefore a promising target in cancer therapy. In the principle of association and ring-opening, we designed and synthesized a series of Hh signaling pathway inhibitors with phenyl imidazole scaffold, which were biologically evaluated in Gli-Luc reporter assay. Compound 25 was identified to possess high potency with nanomolar IC50, and moreover, it preserved the inhibition against wild-type and drug-resistant Smo-overexpressing cells. A molecular modeling study of compound 25 expounded its binding mode to Smo receptor, providing a basis for the further structural modification of phenyl imidazole analogs.

Cannabidiol derivative, preparation method and application thereof

The invention discloses a cannabidiol derivative, a preparation method and application thereof, and belongs to the technical field of medicinal chemistry, wherein the cannabidiol derivative is obtained by taking cannabidiol as a main body through a synthesis means, and an anti-tumor activity determination result shows that the cannabidiol derivative prepared by the invention has an inhibition effect on lung cancer cell strains, human breast cancer cell strains, nasopharynx cancer and drug-resistant strains thereof.