32123-84-5

Basic information

• Product Name: Methyl(α-methylenebenzyl) ketone
• Synonyms: 3-Phenyl-3-buten-2-one;Methyl(α-methylenebenzyl) ketone;Nsc291306
• CAS NO: 32123-84-5
• Molecular Formula: C₁₀H₁₀O
• Molecular Weight: 146.188
• Mol File: 32123-84-5.mol
• Article Data: 27

Chemical Properties

• Boiling Point: 271.4 °C at 760 mmHg
• Flash Point: 97.1 °C
• Appearance: /
• Density: 0.981 g/cm³
• Vapor Pressure: 0.00646mmHg at 25°C
• Refractive Index: 1.518
• CAS DataBase Reference: Methyl(α-methylenebenzyl) ketone(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl(α-methylenebenzyl) ketone(32123-84-5)
• EPA Substance Registry System: Methyl(α-methylenebenzyl) ketone(32123-84-5)

Safety Data

• Hazardous Substances Data: 32123-84-5(Hazardous Substances Data)

Usage

Uses

3-Phenyl-3-buten-2-one is used as odorant, for masking, scenting, and odorization of hydrocarbon oils, fuels, and petroleum products.

InChI:InChI=1/C10H10O/c1-8(9(2)11)10-6-4-3-5-7-10/h3-7H,1H2,2H3

Upstream product

• 76605-87-3 2-Hydroxy-2-methyl-4-nitro-3-phenyl-butyronitrile 
• 769-59-5 3-phenyl-butan-2-one 
• 111-34-2 -butyl vinyl ether 
• 1431-79-4 4,4-dimethyl-2-bromocyclohex-2-en-1-one 
• 30354-18-8 N,N-dimethyl(methylene)ammonium chloride 
• 103-79-7 1-phenyl-acetone 
• 51-80-9 bis-(dimethylamino)methane 
• 98909-26-3 (Hydroxymethyl)(1-methoxy-1-methyl-2-phenyl-2-propenyl)peroxid 
• 119044-25-6 Z-2-phenyl-3-phenylthiobut-2-ene-1-ol 
• 119044-24-5 (E)-2-phenyl-3-phenylthio-but-2-ene-1-ol 
• 98-81-7 1-bromovinylbenzene 
• 108-24-7 acetic anhydride 
• 107454-91-1 1-nitro-2-phenyl-2,3-epoxybutane 
• 873-55-2 sodium benzenesulfonate 

Downstream Products

• 164468-54-6 [Mo(CH₃COC(CH₂)C₆H₅)3] 
• 1460349-41-0 N-((2S)-3-phenylbut-3-en-2-yl)acetamide 
• 1460349-40-9 N-((2R)-3-phenylbut-3-en-2-yl)acetamide 
• 1007-71-2 1-(1-phenyl-cyclopropyl)-ethanone 
• 6249-81-6 3-phenyl-but-3-en-2-ol 
• 129646-78-2 (S)-(+)-3-phenyl-3-buten-2-ol 

Relevant articles and documents

Asymmetric Catalytic Epoxidation of Terminal Enones for the Synthesis of Triazole Antifungal Agents

An enantioselective epoxidation of α-substituted vinyl ketones was realized to construct the key epoxide intermediates for the synthesis of various triazole antifungal agents. The reaction proceeded efficiently in high yields with good enantioselectivities by employing a chiral N,N′-dioxide/ScIII complex as the chiral catalyst and 35% aq. H2O2 as the oxidant. It enabled the facile transformation for optically active isavuconazole, efinaconazole, and other potential antifungal agents.

Bromomethyl Silicate: A Robust Methylene Transfer Reagent for Radical-Polar Crossover Cyclopropanation of Alkenes

A general protocol for visible-light-induced cyclopropanation of alkenes was developed with bromomethyl silicate as a methylene transfer reagent, offering a robust tool for accessing highly valuable cyclopropanes. In addition to α-aryl or methyl-substituted Michael acceptors and styrene derivatives, the unactivated 1,1-dialkyl ethylenes were also shown to be viable substrates. Apart from realizing the cyclopropanation of terminal alkenes, the methyl transfer reaction has been further demonstrated to be amenable to the internal olefins. The photocatalytic cyclopropanation of 1,3-bis(1-arylethenyl)benzenes was also achieved, giving polycyclopropane derivatives in excellent yields. With late-stage cyclopropanation as the key strategy, the synthetic utility of this transformation was also demonstrated by the total synthesis of LG100268.

Enantioselective Bromolactonization of Trisubstituted Olefinic Acids Catalyzed by Chiral Pyridyl Phosphoramides

Enantioselective bromolactonization of trisubstituted olefinic acids producing synthetically useful chiral lactones with two contiguous asymmetric centers has remained mainly unexplored except for the 6-exo cyclization mode. In this work, the 5-exo- and 6