3228-51-1Relevant articles and documents
Preparation of L-threoninol and its bisoxazoline derivative
Lutsenko, Serghey,Jacobsson, Ulla,Moberg, Christina
, p. 661 - 666 (2003)
(R,R)-Threoninol was prepared in one step from L-threonine in 86% isolated yield. The product was regioselectively transformed into 2,2-bis[(4R,5R)4-(hydroxymethyl)-5-methyl-1,3-oxazolin-2-yl]propane in 42% isolated yield.
Heterogeneous Catalytic Hydrogenation of Chiral Amino Acid Methyl Esters to Amino Alcohols with Retention of Configuration Over Mg-Modified Cu/ZnO/Al2O3 Catalyst
Zhan, Bing,Zhang, Shuangshuang,Yu, Jun,Xiao, Xiuzheng,Guo, Xiaoming,Mao, Dongsen,Lu, Guanzhong
, p. 2160 - 2166 (2017/07/25)
Selective hydrogenation of amino acid methyl esters to chiral amino alcohols is an important and fascinating process. The CuZn0.3Mg0.1AlOx catalyst for the synthesis of chiral amino alcohols was prepared by the fractional
Stereoselective synthesis and anti-inflammatory activities of 6- and 7-membered dioxacycloalkanes
Gu, Keli,Bi, Lanrong,Zhao, Ming,Wang, Chao,Dolan, Cheryl,Kao, Michael C.,Tok, Jeffrey B.-H.,Peng, Shiqi
, p. 1339 - 1347 (2007/10/03)
A class of 5-trifluoroacetylamino-1,3-dioxacycloalkanes, 5-benzoylamino-1,3-dioxacycloalkanes, and 5-amino-1,3-dioxacycloalkane compounds were stereoselectively synthesized as potential anti-inflammatory drug candidates. The anti-inflammatory activities of these compounds were tested using the xylene-induced mouse ear edema model, from which multiple compounds possessing anti-inflammatory properties which surpass aspirin were identified; these compounds were then compared to establish structure-activity relationships.
