32358-83-1

Basic information

• Product Name: naphtho(1,2-b)furan-4,5-dione
• Synonyms: naphtho(1,2-b)furan-4,5-dione
• CAS NO: 32358-83-1
• Molecular Formula: C₁₂H₆O₃
• Molecular Weight: 198.17
• Mol File: 32358-83-1.mol
• Article Data: 8

Chemical Properties

• Melting Point: 213-215 °C
• Boiling Point: 372.7°C at 760 mmHg
• Flash Point: 176.9°C
• Appearance: /
• Density: 1.396g/cm³
• Vapor Pressure: 9.43E-06mmHg at 25°C
• Refractive Index: 1.637
• CAS DataBase Reference: naphtho(1,2-b)furan-4,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: naphtho(1,2-b)furan-4,5-dione(32358-83-1)
• EPA Substance Registry System: naphtho(1,2-b)furan-4,5-dione(32358-83-1)

Safety Data

• Hazardous Substances Data: 32358-83-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H6O3/c13-10-7-3-1-2-4-8(7)12-9(11(10)14)5-6-15-12/h1-6H

Upstream product

• 858019-74-6 2-hydroxy-3-vinyl-[1,4]naphthoquinone 
• 148839-41-2 2-o-Tolyl-furan-3-carboxylic acid diethylamide 
• 82423-03-8 2-(1-hydroxy-1-methylethyl)-2,3-dihydronaphtho[1,2-b]furan-4,5-dione 
• 83-72-7 2-hydroxynaphtho-1,4-quinone 
• 107-20-0 2-chloroethanal 
• 1198104-22-1 naphtho[1,2-b]furan-4-ol 
• 84-79-7 Lapachol 
• 13196-10-6 benzofuran-5-ol 
• 106-99-0 buta-1,3-diene 

Downstream Products

• 1192373-15-1 2-(4-formylphenyl)furo[3',2':3,4]naphtho[1,2-d]imidazole 
• 1192373-14-0 2-(4-nitrophenyl)furo[3',2':3,4]naphtho[1,2-d]imidazole 
• 1192373-13-9 2-phenylfuro[3',2':3,4]naphtho[1,2-d]imidazole 

Relevant articles and documents

Facile synthesis of avicequinone-B natural product

An efficient synthesis of avicequinone-B (2) and furonaphthoquinone 4 has been carried out starting from 2-hydroxy-1,4-naphthoquinone (6) by CAN-mediated cycloaddition reaction.

Applications of naphtho[1,2-b]furan-4,5-diketone-2-sulfonic acid derivative and salt thereof in preparation of antitumor drugs

The invention discloses applications of a naphtho[1,2-b]furan-4,5-diketone-2-sulfonic acid derivative and a salt thereof in preparation of antitumor drugs, wherein the chemical structure formula of the naphtho[1,2-b]furan-4,5-diketone-2-sulfonic acid derivative is represented by a general formula (I), the general formula (I) is defined in the specification, R1 , R2, R3 and R4 are respectively and independently selected from hydrogen and halogen, and R5 is independently selected hydrogen, halogen, C1-C5 alkyl, and aryl. According to the present invention, the structure of the parent compound is modified, such that the water solubility of the compound is improved, and the good antitumor activity is provided.

Studies on polynuclear furoquinones. Part 1: Synthesis of tri- and tetra-cyclic furoquinones simulating BCD/ABCD ring system of furoquinone diterpenoids

Synthesis of phenanthro[1,2-b]furan-10,11-dione, the core nucleus present in Tanshinone-I is described in 8-10 steps starting from 2-bromo-3,4-dihydro-1- naphthaldehyde. The bromoaldehyde was converted to methyl 2-(2-bromo-1-naphthyl) acetate or 2-(2- bro